Evidence map›Paper›PMID 34220755›Full record

ArticleFrontiers in microbiology2021

Lactosmart: A Novel Therapeutic Molecule for Antimicrobial Defense.

Jiya Singh, Viswanathan Vijayan, Saiema Ahmedi, Pradeep Pant, Nikhat Manzoor, Tej P Singh, Pradeep Sharma, Sujata Sharma

RetractedOpen access · goldAbstract readRetracted Publication
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jiya SinghDepartment of Biophysics, All India Institute of Medical Sciences, New Delhi, India.
Viswanathan VijayanDepartment of Biophysics, All India Institute of Medical Sciences, New Delhi, India.
Saiema AhmediDepartment of Biosciences, Jamia Millia Islamia, New Delhi, India.
Pradeep PantDepartment of Chemistry, Indian Institute of Technology Delhi, New Delhi, India.
Nikhat ManzoorDepartment of Biosciences, Jamia Millia Islamia, New Delhi, India.
Tej P SinghDepartment of Biophysics, All India Institute of Medical Sciences, New Delhi, India.
Pradeep SharmaDepartment of Biophysics, All India Institute of Medical Sciences, New Delhi, India.
Sujata SharmaDepartment of Biophysics, All India Institute of Medical Sciences, New Delhi, India.
All India Institute of Medical Sciences · INJamia Millia Islamia · INIndian Institute of Technology Delhi · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The problem of antibiotic resistance has prompted researchers around the globe to search for new antimicrobial agents. Antimicrobial proteins and peptides are naturally secreted by almost all the living organisms to fight infections and can be safer alternatives to chemical antibiotics. Lactoferrin (LF) is a known antimicrobial protein present in all body secretions. In this study, LF was digested by trypsin, and the resulting hydrolysates were studied with respect to their antimicrobial properties. Among the hydrolysates, a 21-kDa basic fragment of LF (termed lactosmart) showed promise as a new potent antimicrobial agent. The antimicrobial studies were performed on various microorganisms including

Indexed as

antibacterialantifungalbiofilmlactoferrinLPSSPR

Identifiers

PMID34220755
PMCPMC8250155
OpenAlexW3174245297

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.