ArticleFrontiers in microbiology2021
Using Structural Equation Modeling to Understand Interactions Between Bacterial and Archaeal Populations and Volatile Fatty Acid Proportions in the Rumen.
Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 50 citations in OpenAlex.
- Comparative metataxonomic analysis of total, viable, and active rumen microbial communities under methane-mitigated conditions.Environmental microbiome · 2026Article
- Breed-specific microbiomes drive differential responses to 3-nitrooxypropanol andJDS communications · 2026Article
- Biophotocatalytic and bioelectrocatalytic strategies for methane production and oxidation: emerging pathways and perspectives.Archives of microbiology · 2026Review
- A review on the use of coconut oil to mitigate methane emissions in ruminants: mechanisms of action and research progress.Frontiers in veterinary science · 2026Review
- Investigating the antimethanogenic effects of selected nitro-compounds on methane production, rumen fermentation, and methanogenic archaeaApplied and environmental microbiology · 2025Article
- Host-specific microbiome-rumination interactions shape methane-yield phenotypes in dairy cattle.mSphere · 2025Article
- Assessment of fecal bacterial viability and diversity in fresh and frozen fecal microbiota transplant (FMT) product in horses.BMC veterinary research · 2024Article
- Effects of Electrolyte Multivitamins and Neomycin on Immunity and Intestinal Barrier Function in Transported Lambs.Animals : an open access journal from MDPI · 2024Article
- Establishment of methanogen bacterial interactions during the preweaning period of dairy cattle.PloS one · 2024Article
- Article
- Screening macroalgae for mitigation of enteric methane in vitro.Scientific reports · 2023Article
- The effect of 3-nitrooxypropanol, a potent methane inhibitor, on ruminal microbial gene expression profiles in dairy cows.Microbiome · 2022Article
- Microbiological insights into anaerobic digestion for biogas, hydrogen or volatile fatty acids (VFAs): a review.Bioengineered · 2022Review
- Comparing noninvasive sampling techniques with standard cannula sampling method for ruminal microbial analysis.JDS communications · 2021Article
Corrections and comments
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Authors and funding
15 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microbial syntrophy (obligate metabolic mutualism) is the hallmark of energy-constrained anaerobic microbial ecosystems. For example, methanogenic archaea and fermenting bacteria coexist by interspecies hydrogen transfer in the complex microbial ecosystem in the foregut of ruminants; however, these synergistic interactions between different microbes in the rumen are seldom investigated. We hypothesized that certain bacteria and archaea interact and form specific microbial cohorts in the rumen. To this end, we examined the total (DNA-based) and potentially metabolically active (cDNA-based) bacterial and archaeal communities in rumen samples of dairy cows collected at different times in a 24 h period. Notably, we found the presence of distinct bacterial and archaeal networks showing potential metabolic interactions that were correlated with molar proportions of specific volatile fatty acids (VFAs). We employed hypothesis-driven structural equation modeling to test the significance of and to quantify the extent of these relationships between bacteria-archaea-VFAs in the rumen. Furthermore, we demonstrated that these distinct microbial networks were host-specific and differed between cows indicating a natural variation in specific microbial networks in the rumen of dairy cows. This study provides new insights on potential microbial metabolic interactions in anoxic environments that have broader applications in methane mitigation, energy conservation, and agricultural production.
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