Evidence map›Paper›PMID 34220714›Full record

ArticleFrontiers in endocrinology2021

ZYG11A Is Expressed in Epithelial Ovarian Cancer and Correlates With Low Grade Disease.

Laris Achlaug, Lina Somri-Gannam, Shilhav Meisel-Sharon, Rive Sarfstein, Manisha Dixit, Shoshana Yakar, Mordechai Hallak, Zvi Laron, Haim Werner, Ilan Bruchim

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Laris AchlaugDepartment of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Lina Somri-GannamGynecology Oncology Laboratory, Department of Obstetrics and Gynecology, Hillel Yaffe Medical Center, Hadera, Israel.
Shilhav Meisel-SharonGynecology Oncology Laboratory, Department of Obstetrics and Gynecology, Hillel Yaffe Medical Center, Hadera, Israel.
Rive SarfsteinDepartment of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Manisha DixitDavid B. Kriser Dental Center, Department of Basic Science and Craniofacial Biology, New York University College of Dentistry, New York, NY, United States.
Shoshana YakarDavid B. Kriser Dental Center, Department of Basic Science and Craniofacial Biology, New York University College of Dentistry, New York, NY, United States.
Mordechai HallakGynecology Oncology Laboratory, Department of Obstetrics and Gynecology, Hillel Yaffe Medical Center, Hadera, Israel.
Zvi LaronEndocrine and Diabetes Research Unit, Schneider Children's Medical Center, Petah Tikva, Israel.
Haim WernerDepartment of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Ilan BruchimGynecology Oncology Laboratory, Department of Obstetrics and Gynecology, Hillel Yaffe Medical Center, Hadera, Israel.
Hillel Yaffe Medical Center · ILTel Aviv University · ILNew York University · USSchneider Children's Medical Center · ILTechnion – Israel Institute of Technology · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The insulin-like growth factors (IGF) are important players in the development of gynecological malignancies, including epithelial ovarian cancer (EOC). The identification of biomarkers that can help in the diagnosis and scoring of EOC patients is of fundamental importance in clinical oncology. We have recently identified the

Indexed as

AdultAgedAged, 80 and overAnimalsCarcinoma, Ovarian EpithelialCell Cycle ProteinsFemaleGene Expression Regulation, NeoplasticHumansMiceMiddle AgedNeoplasm GradingOvarian NeoplasmsOvaryReceptor, IGF Type 1Tumor Suppressor Protein p53Cell Cycle ProteinsIGF1R protein, humanReceptor, IGF Type 1Tumor Suppressor Protein p53ZYG11A protein, humanIGF1 receptorinsulin-like growth factor-1 (IGF1)ovarian cancerp53ZYG11A

Identifiers

PMID34220714
PMCPMC8249937
OpenAlexW3173977832

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.