Evidence map›Paper›PMID 34220684›Full record

ArticleFrontiers in neurology2021

Early Effects of Passive Leg-Raising Test, Fluid Challenge, and Norepinephrine on Cerebral Autoregulation and Oxygenation in COVID-19 Critically Ill Patients.

Chiara Robba, Antonio Messina, Denise Battaglini, Lorenzo Ball, Iole Brunetti, Matteo Bassetti, Daniele R Giacobbe, Antonio Vena, Nicolo' Patroniti, Maurizio Cecconi and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Review
  4. Observational
  5. Article
  6. Review
  7. Observational
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 3 countries.

Chiara RobbaDepartment of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy.
Antonio MessinaHumanitas Clinical and Research Center-Istituto di Ricovero e Cura a Carattere Scientifico, Milan, Italy.
Denise BattagliniSan Martino Policlinico Hospital, Istituto di Ricovero e Cura a Carattere Scientifico for Oncology and Neuroscience, Genoa, Italy.
Lorenzo BallDepartment of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy.
Iole BrunettiSan Martino Policlinico Hospital, Istituto di Ricovero e Cura a Carattere Scientifico for Oncology and Neuroscience, Genoa, Italy.
Matteo BassettiDepartment of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
Daniele R GiacobbeDepartment of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
Antonio VenaInfectious Diseases Unit, San Martino Policlinico Hospital, Genoa, Italy.
Nicolo' PatronitiDepartment of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy.
Maurizio CecconiHumanitas Clinical and Research Center-Istituto di Ricovero e Cura a Carattere Scientifico, Milan, Italy.
Basil F MattaNeurocritical Care Unit, Addenbrookes Hospital, Cambridge, United Kingdom.
Xiuyun LiuDepartment of Anesthesiology and Critical Care Medicine, John Hopkins University, Baltimore, MD, United States.
Patricia R M RoccoLaboratory of Pulmonary Investigation, Carlos Chagas Filho Institute of Biophysics, Rio de Janeiro, Brazil.
Marek CzosnykaBrain Physics Laboratory, Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom.
Paolo PelosiDepartment of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy.
Ospedale Policlinico San Martino · ITUniversity of Genoa · ITHumanitas University · ITAddenbrooke's Hospital · GBFundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro · BRUniversity of Cambridge · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cerebral autoregulationcerebral oxygenationfluid challengenorepinephrinepassive leg raising test

Identifiers

PMID34220684
PMCPMC8242251
OpenAlexW3169811340

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.