ArticleFrontiers in physiology2021
Cuff-Method Thigh Arterial Occlusion Counteracts Cerebral Hypoperfusion Against the Push-Pull Effect in Humans.
Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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10 authors at 1 institution in 1 country.
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Abstract
Exposure to acute transition from negative (-Gz) to positive (+ Gz) gravity significantly impairs cerebral perfusion in pilots of high-performance aircraft during push-pull maneuver. This push-pull effect may raise the risk for loss of vision or consciousness. The aim of the present study was to explore effective countermeasures against cerebral hypoperfusion induced by the push-pull effect. Twenty healthy young volunteers (male, 21 ± 1 year old) were tested during the simulated push-pull maneuver by tilting. A thigh cuff (TC) pressure of 200 mmHg was applied before and during simulated push-pull maneuver (-0.87 to + 1.00 Gz). Beat-to-beat cerebral and systemic hemodynamics were measured continuously. During rapid -Gz to + Gz transition, mean cerebral blood flow velocity (CBFV) was decreased, but to a lesser extent, in the TC bout compared with the control bout (-3.1 ± 4.9 vs. -7.8 ± 4.4 cm/s,
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