Evidence map›Paper›PMID 34220488›Full record

ArticleFrontiers in aging neuroscience2021

Long-Term Increase in Cholesterol Is Associated With Better Cognitive Function: Evidence From a Longitudinal Study.

Huamin Liu, Lianwu Zou, Rui Zhou, Minyi Zhang, Shanyuan Gu, Jiazhen Zheng, Daniel Nyarko Hukportie, Keyi Wu, Zhiwei Huang, Zelin Yuan and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 49 citations in OpenAlex.

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  11. Dyslipidemia and cerebral atrophy among health check-up individuals: A cross-sectional study.International journal of cardiology. Cardiovascular risk and prevention · 2025
    Article
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  13. Review
  14. Causal mediation analysis of the neuroprotection ofmedRxiv : the preprint server for health sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Huamin LiuDepartment of Epidemiology, School of Public Health, Southern Medical University, Guangzhou, China.
Lianwu ZouDepartment of Psychiatry, Baiyun Psychiatric Rehabilitation Hospital, Guangzhou, China.
Rui ZhouDepartment of Epidemiology, School of Public Health, Southern Medical University, Guangzhou, China.
Minyi ZhangDepartment of Epidemiology, School of Public Health, Southern Medical University, Guangzhou, China.
Shanyuan GuInpatient Department, Baiyun Psychiatric Rehabilitation Hospital, Guangzhou, China.
Jiazhen ZhengDepartment of Epidemiology, School of Public Health, Southern Medical University, Guangzhou, China.
Daniel Nyarko HukportieDepartment of Epidemiology, School of Public Health, Southern Medical University, Guangzhou, China.
Keyi WuDepartment of Epidemiology, School of Public Health, Southern Medical University, Guangzhou, China.
Zhiwei HuangDepartment of Epidemiology, School of Public Health, Southern Medical University, Guangzhou, China.
Zelin YuanDepartment of Epidemiology, School of Public Health, Southern Medical University, Guangzhou, China.
Xianbo WuDepartment of Epidemiology, School of Public Health, Southern Medical University, Guangzhou, China.
Southern Medical University · CNGuangzhou Psychiatric Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cholesterolcognitive declineepisodic memorylongitudinal studymental intactness

Identifiers

PMID34220488
PMCPMC8248815
OpenAlexW3176382416

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.