Evidence map›Paper›PMID 34220288›Full record

ArticleMaterials today (Kidlington, England)2021

3D Printing in alloy design to improve biocompatibility in metallic implants.

Indranath Mitra, Susmita Bose, William S Dernell, Nairanjana Dasgupta, Chrissy Eckstrand, Jim Herrick, Michael J Yaszemski, Stuart B Goodman, Amit Bandyopadhyay

Open access · greenAbstract read
In one paragraph

Article in Materials today (Kidlington, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 3 pooled it
9.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 3 syntheses or guidelines pooled it, 165 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Article
  6. Article
  7. ZnO-Hydroxyapatite-Coated Ti-6Al-4V With Curcumin and Ginger Extract for Load-Bearing Implants.Journal of the American Ceramic Society. American Ceramic Society · 2026
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. EnhancedACS applied bio materials · 2025
    Article
  14. Review
  15. Article
  16. Article
  17. Application of custom-made joint prostheses in wrist.Journal of Zhejiang University. Science. B · 2025
    Review
  18. Article
  19. Review
  20. Biodegradable poly(caprolactone fumarate) 3D printed scaffolds for segmental bone defects within the Masquelet technique.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Indranath MitraW. M. Keck Biomedical Materials Research Laboratory, School of Mechanical and Materials Engineering, Washington State University, Pullman, WA 99164 2920, USA.
Susmita BoseW. M. Keck Biomedical Materials Research Laboratory, School of Mechanical and Materials Engineering, Washington State University, Pullman, WA 99164 2920, USA.
William S DernellCollege of Veterinary Medicine, Washington State University, Pullman, WA 99164, USA.
Nairanjana DasguptaDepartment of Mathematics and Statistics, Washington State University, Pullman, WA 99164, USA.
Chrissy EckstrandCollege of Veterinary Medicine, Washington State University, Pullman, WA 99164, USA.
Jim HerrickDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.
Michael J YaszemskiDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.
Stuart B GoodmanDepartment of Orthopedic Surgery, Stanford University Medical Center, Redwood City, CA 94063, USA.
Amit BandyopadhyayW. M. Keck Biomedical Materials Research Laboratory, School of Mechanical and Materials Engineering, Washington State University, Pullman, WA 99164 2920, USA.
Washington State University · USMayo Clinic in Arizona · USStanford Medicine · US

Funding

3D Printed Surface Modified Porous Metal Coatings for Load-Bearing ImplantsR01AR067306 · NIAMS · WASHINGTON STATE UNIVERSITY · PI BANDYOPADHYAY, AMIT · 2015 to 2019
$1.8M
NIAMS NIH HHS R01 AR067306
6 · The paper itself

Abstract

3D Printing (3DP) or additive manufacturing (AM) enables parts with complex shapes, design flexibility, and customization opportunities for defect specific patient-matched implants. 3DP or AM also offers a design platform that can be used to innovate novel alloys for application-specific compositional modifications. In medical applications, the biological response from a host tissue depends on a biomaterial's structural and compositional properties in the physiological environment. Application of 3DP can pave the way towards manufacturing innovative metallic implants, combining structural variations at different length scales and tailored compositions designed for specific biological responses. This study shows how 3DP can be used to design metallic alloys for orthopedic and dental applications with improved biocompatibility using

Identifiers

PMID34220288
PMCPMC8248902
OpenAlexW3129155609

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.