Evidence map›Paper›PMID 34220191›Full record

ArticleInfectious diseases in obstetrics and gynecology2021

Antibacterial and Antifungal Activity of the Human Endometrial Fluid during the Natural Cycle.

Marta Bregón-Villahoz, Maria-Dolores Moragues, Inés Arrieta-Aguirre, Mikel Azkargorta, Lucía Lainz, Miren Diez-Zapirain, Maria Iglesias, Maria-Begoña Prieto, Ana Matorras, Antonia Exposito and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Infectious diseases in obstetrics and gynecology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Marta Bregón-VillahozDepartment of Nursing, Faculty of Medicine and Nursing, University of the Basque Country UPV/EHU, Barrio Sarriena s/n, 48940-Leioa, Spain.ORCID 0000-0003-2196-272X
Maria-Dolores MoraguesDepartment of Nursing, Faculty of Medicine and Nursing, University of the Basque Country UPV/EHU, Barrio Sarriena s/n, 48940-Leioa, Spain.ORCID 0000-0002-7272-8610
Inés Arrieta-AguirreDepartment of Nursing, Faculty of Medicine and Nursing, University of the Basque Country UPV/EHU, Barrio Sarriena s/n, 48940-Leioa, Spain.ORCID 0000-0002-2593-2221
Mikel AzkargortaProteomics Platform, CIC bioGUNE, CIBERehd, ProteoRed-ISCIII, Bizkaia Science and Technology Park, Derio, Spain.ORCID 0000-0001-9115-3202
Lucía LainzHuman Reproduction Unit, Cruces University Hospital, University of the Basque Country, Barakaldo, Spain.
Miren Diez-ZapirainHuman Reproduction Unit, Cruces University Hospital, University of the Basque Country, Barakaldo, Spain.
Maria IglesiasHuman Reproduction Unit, Cruces University Hospital, University of the Basque Country, Barakaldo, Spain.
Maria-Begoña PrietoHuman Reproduction Unit, Cruces University Hospital, University of the Basque Country, Barakaldo, Spain.
Ana MatorrasFacultad de Medicina, Universidad Europea de Madrid, Villaviciosa de Odon, Madrid, Spain.
Antonia ExpositoHuman Reproduction Unit, Cruces University Hospital, University of the Basque Country, Barakaldo, Spain.
Felix ElortzaProteomics Platform, CIC bioGUNE, CIBERehd, ProteoRed-ISCIII, Bizkaia Science and Technology Park, Derio, Spain.ORCID 0000-0001-8839-5438
Roberto MatorrasHuman Reproduction Unit, Cruces University Hospital, University of the Basque Country, Barakaldo, Spain.ORCID 0000-0002-4279-6823
University of the Basque Country · ESInstituto de Salud Carlos III · ESUniversidad Europea de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Some microbiota patterns have been associated with favorable IVF prognosis and others with pathological conditions. The endometrial fluid aspirate (EFA) contains antibacterial proteins that are enriched in implantative IVF cycles, but the antimicrobial effect of EFA has not been addressed. We aimed to evaluate the antimicrobial activity of the human endometrial fluid during the natural cycle. Methods: EFA was obtained through an embryo transfer catheter in 38 women, aged 18-40 years, with regular cycles attending to a fertility clinic. The antimicrobial activity of EFAs was tested against two strains of Results: All samples exhibited antibacterial activity against Conclusions: EFA presented two antimicrobial activity patterns: (a) one common to all the samples, exhibiting activity against

Indexed as

Antifungal AgentsAnti-Infective AgentsAnti-Bacterial AgentsEscherichia coliFemaleHumansMicrobial Sensitivity TestsPichiaStaphylococcus aureusAnti-Bacterial AgentsAntifungal AgentsAnti-Infective Agents

Identifiers

PMID34220191
PMCPMC8221874
OpenAlexW3168742945

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.