ReviewActa clinica Croatica2020
Prophylactic Central Neck Dissection in Well-differentiated Thyroid Cancer.
Review in Acta clinica Croatica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Risk factors for death of follicular thyroid carcinoma: a systematic review and meta-analysis.Endocrine · 2023Pooled it
- Observational
- Triumph Over Butchery: Guest Editorial for Indian Journal of Surgical Oncology.Indian journal of surgical oncology · 2025Article
- Article
- The role of intraoperative central lymph node biopsy in the treatment of clinically low-risk PTMC.Endocrine · 2024Article
- Article
- Demographic, clinical, and surgical features of patients undergoing thyroidectomy due to thyroid lesions in Southern Iran: A cross-sectional study.Health science reports · 2024Article
- Techniques for Thyroidectomy and Functional Neck Dissection.Journal of clinical medicine · 2024Review
- Transcription factor FOXP4 inversely governs tumor suppressor genes and contributes to thyroid cancer progression.Heliyon · 2024Article
- Transoral endoscopic and robotic thyroidectomy for thyroid cancer: the mid-term oncological outcome.Surgical endoscopy · 2023Article
- Role of prophylactic central neck lymph node dissection for papillary thyroid carcinoma in the era of de-escalation.World journal of clinical oncology · 2023Review
- Construction of prediction models for determining the risk of lateral lymph node metastasis in patients with thyroid papillary carcinoma based on gender stratification.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023Article
- Sentinel lymph node mapping: current applications and future perspectives in thyroid carcinoma.Frontiers in medicine · 2023Review
- En bloc resection of total thyroid and bilateral central compartment lymph nodesFrontiers in endocrinology · 2023Article
- The co-occurrence of both breast- and differentiated thyroid cancer: incidence, association and clinical implications for daily practice.BMC cancer · 2022Article
- Risk factors of cervical lymph node metastasis in multifocal papillary thyroid cancer.Frontiers in oncology · 2022Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Well-differentiated cancers, both papillary and follicular, account for 90% of all diagnosed thyroid cancers. They have an indolent disease course with a 20-year disease-specific survival over 90%. According to current guidelines, the therapy of choice for well-differentiated thyroid carcinoma is total thyroidectomy or lobectomy. The indication for prophylactic central neck dissection is still a controversial issue and the subject of unfinished and ongoing debate. There is no indication for prophylactic central neck dissection in follicular thyroid carcinomas, which primarily metastasize hematogenously. In small solitary papillary thyroid carcinomas (T1 and T2), prophylactic central neck dissection is not indicated as it does not bring benefits in terms of improved patient survival and at the same time significantly increases the risk of temporary and permanent postoperative complications. Prophylactic central neck dissection is indicated in advanced papillary thyroid cancers (T3 and T4) and all other high-risk well-differentiated thyroid cancer, as well as in the presence of metastatic lymph nodes in the lateral neck.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.