Evidence map›Paper›PMID 34219726›Full record

ArticleJournal of Alzheimer's disease : JAD2021

Documentation of Dementia as a Cause of Death Among Mexican-American Decedents Diagnosed with Dementia.

Brian Downer, Lin-Na Chou, Soham Al Snih, Cheyanne Barba, Yong-Fang Kuo, Mukaila Raji, Kyriakos S Markides, Kenneth J Ottenbacher

Open access · greenAbstract read
In one paragraph

Article in Journal of Alzheimer's disease : JAD, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Brian DownerDivision of Rehabilitation Sciences, School of Health Professions, University of Texas Medical Branch, Galveston, TX, USA.
Lin-Na ChouPreventive Medicine and Population Health, University of Texas Medical Branch, Galveston, TX, USA.
Soham Al SnihDivision of Rehabilitation Sciences, School of Health Professions, University of Texas Medical Branch, Galveston, TX, USA.
Cheyanne BarbaDepartment of Psychology, University of Alabama at Birmingham, Birmingham, AL, USA.
Yong-Fang KuoSealy Center on Aging, University of Texas Medical Branch, Galveston, TX, USA.
Mukaila RajiSealy Center on Aging, University of Texas Medical Branch, Galveston, TX, USA.
Kyriakos S MarkidesSealy Center on Aging, University of Texas Medical Branch, Galveston, TX, USA.
Kenneth J OttenbacherDivision of Rehabilitation Sciences, School of Health Professions, University of Texas Medical Branch, Galveston, TX, USA.
The University of Texas Medical Branch at Galveston · USUniversity of Alabama at Birmingham · US

Funding

UTMB OAIC Research Education Component (REC)P30AG024832 · NIA · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI JAMES S. GOODWIN, MD, MELISSA M. MORROW · 2005 to 2026
$26.7M
LONGITUDINAL STUDY OF MEXICAN AMERICAN ELDERLY HEALTHR01AG010939 · NIA · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI MARKIDES, KYRIAKOS S · 1992 to 2022
$14.6M
The Texas Resource Center on Minority Aging Research (RCMAR)P30AG059301 · NIA · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Kyriakos S Markides, Fernando Riosmena · 2018 to 2026
$5.2M
Aging in Puerto Rico: Longitudinal Follow-Up of the PREHCO StudyR01AG064769 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CROWE, MICHAEL GABRIEL · 2019 to 2023
$3.5M
Long-term Health Outcomes in Mexican American Older AdultsR01MD010355 · NIMHD · UNIVERSITY OF TEXAS MED BR GALVESTON · PI AL SNIH, SOHAM · 2016 to 2019
$1.9M
Improvement in Patients' Cognition and Relationship with SNF Quality MeasuresK01AG058789 · NIA · UNIVERSITY OF TEXAS MED BR GALVESTON · PI DOWNER, BRIAN GREGORY · 2019 to 2023
$613k
NIA NIH HHS K01 AG058789NIA NIH HHS P30 AG024832NIA NIH HHS P30 AG059301NIA NIH HHS R01 AG010939NIA NIH HHS R01 AG064769NIMHD NIH HHS R01 MD010355
6 · The paper itself

Abstract

backgroundHispanic older adults are a high-risk population for Alzheimer's disease and related dementias (ADRD) but are less likely than non-Hispanic White older adults to have ADRD documented as a cause of death on a death certificate.

objectiveTo investigate characteristics associated with ADRD as a cause of death among Mexican-American decedents diagnosed with ADRD.

methodsData came from the Hispanic Established Populations for the Epidemiologic Study of the Elderly, Medicare claims, and National Death Index.

resultsThe final sample included 853 decedents diagnosed with ADRD of which 242 had ADRD documented as a cause of death. More health comorbidities (OR = 0.40, 95% CI = 0.28-0.58), older age at death (OR = 1.18, 95% CI = 1.03-1.36), and longer ADRD duration (OR = 1.08, 95% CI = 1.03-1.14) were associated with ADRD as a cause of death. In the last year of life, any ER admission without a hospitalization (OR = 0.45, 95% CI = 0.22-0.92), more physician visits (OR = 0.96, 95% CI = 0.93-0.98), and seeing a medical specialist (OR = 0.46, 95% CI = 0.29-0.75) were associated with lower odds for ADRD as a cause of death. In the last 30 days of life, any hospitalization with an ICU stay (OR = 0.55, 95% CI = 0.36-0.82) and ER admission with a hospitalization (OR = 0.67, 95% CI = 0.48-0.94) were associated with lower odds for ADRD as a cause of death. Receiving hospice care in the last 30 days of life was associated with 1.98 (95% CI = 1.37-2.87) higher odds for ADRD as a cause of death.

conclusionUnder-documentation of ADRD as a cause of death may reflect an underestimation of resource needs for Mexican-Americans with ADRD.

Indexed as

Cause of DeathComorbidityAged, 80 and overAge FactorsDementiaDocumentationFemaleHospicesHospitalizationHumansInsurance Claim ReviewMaleMedicareMexican AmericansUnited StatesCause of deathhealth serviceshispanic Americansmortality

Identifiers

PMID34219726
PMCPMC8384698
OpenAlexW3175853923

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.