Evidence map›Paper›PMID 34219663›Full record

ArticleEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology2022

Balloon pulmonary angioplasty in chronic thromboembolic pulmonary hypertension: a multicentre registry.

Szymon Darocha, Marek Roik, Grzegorz Kopeć, Aleksander Araszkiewicz, Michał Furdal, Maciej Lewandowski, Wojciech Jacheć, Marek Grabka, Marta Banaszkiewicz, Arkadiusz Pietrasik and 24 more

Registry-linked trialOpen access · greenAbstract readMulticenter Study
In one paragraph

Article in EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03959748 (DataBase of pulmoNary hyPertesion in PoLish Population - BNP-PL), which is not on this map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03959748 recruitingnot on this map

DataBase of pulmoNary hyPertesion in PoLish Population - BNP-PL

Typeobservational_patient_registrySponsorPolish Cardiology AssociationRan2018 to 2028Enrolled3,000ConditionsChronic Thromboembolic Pulmonary Hypertension, Pulmonary Arterial Hypertension
3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Observational
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Chronic thromboembolic pulmonary disease.The European respiratory journal · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors at 8 institutions in 1 country.

Szymon DarochaDepartment of Pulmonary Circulation, Thromboembolic Diseases and Cardiology, European Health Centre Otwock, Centre of Postgraduate Medical Education, Warsaw, Poland.
Marek RoikDepartment of Internal Medicine and Cardiology, Medical University of Warsaw, Warsaw, Poland.
Grzegorz KopećPulmonary Circulation Centre, Department of Cardiac and Vascular Diseases, Faculty of Medicine, Jagiellonian University Medical College, Centre for Rare Cardiovascular Diseases, John Paul II Hospital in Krakow, Krakow, Poland.
Aleksander Araszkiewicz1st Department of Cardiology, Poznan University of Medical Sciences, Poznan, Poland.
Michał FurdalDepartment of Cardiology, Provincial Specialist Hospital Research and Development Center, Wrocław, Poland.
Maciej LewandowskiClinic of Cardiology, Pomeranian Medical University, Szczecin, Poland.
Wojciech Jacheć2nd Department of Cardiology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, Katowice, Poland.
Marek Grabka1st Department of Cardiology, Silesian Medical University, Upper Silesian Medical Centre, Katowice, Poland.
Marta BanaszkiewiczDepartment of Pulmonary Circulation, Thromboembolic Diseases and Cardiology, European Health Centre Otwock, Centre of Postgraduate Medical Education, Warsaw, Poland.
Arkadiusz PietrasikDepartment of Cardiology, Medical University of Warsaw, Warsaw, Poland.
Radosław PieturaDepartment of Radiography, Medical University of Lublin, Lublin, Poland.
Jakub StępniewskiPulmonary Circulation Centre, Department of Cardiac and Vascular Diseases, Faculty of Medicine, Jagiellonian University Medical College, Centre for Rare Cardiovascular Diseases, John Paul II Hospital in Krakow, Krakow, Poland.
Marcin WaligóraPulmonary Circulation Centre, Department of Cardiac and Vascular Diseases, Faculty of Medicine, Jagiellonian University Medical College, Centre for Rare Cardiovascular Diseases, John Paul II Hospital in Krakow, Krakow, Poland.
Wojciech MagońPulmonary Circulation Centre, Department of Cardiac and Vascular Diseases, Faculty of Medicine, Jagiellonian University Medical College, Centre for Rare Cardiovascular Diseases, John Paul II Hospital in Krakow, Krakow, Poland.
Kamil JonasPulmonary Circulation Centre, Department of Cardiac and Vascular Diseases, Faculty of Medicine, Jagiellonian University Medical College, Centre for Rare Cardiovascular Diseases, John Paul II Hospital in Krakow, Krakow, Poland.
Andrzej ŁabykDepartment of Internal Medicine and Cardiology, Medical University of Warsaw, Warsaw, Poland.
Michał PotępaDepartment of Internal Medicine and Cardiology, Medical University of Warsaw, Warsaw, Poland.
Aleksandra FudrynaDepartment of Internal Medicine and Cardiology, Medical University of Warsaw, Warsaw, Poland.
Stanisław Jankiewicz1st Department of Cardiology, Poznan University of Medical Sciences, Poznan, Poland.
Sylwia Sławek-Szmyt1st Department of Cardiology, Poznan University of Medical Sciences, Poznan, Poland.
Tatiana Mularek-Kubzdela1st Department of Cardiology, Poznan University of Medical Sciences, Poznan, Poland.
Maciej Lesiak1st Department of Cardiology, Poznan University of Medical Sciences, Poznan, Poland.
Ewa MroczekDepartment of Cardiology, Provincial Specialist Hospital Research and Development Center, Wrocław, Poland.
Joanna OrłowskaDepartment of Cardiology, Provincial Specialist Hospital Research and Development Center, Wrocław, Poland.
Małgorzata Peregud-PogorzelskaClinic of Cardiology, Pomeranian Medical University, Szczecin, Poland.
Andrzej Tomasik2nd Department of Cardiology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, Katowice, Poland.
Katarzyna Mizia-Stec1st Department of Cardiology, Silesian Medical University, Upper Silesian Medical Centre, Katowice, Poland.
Roman PrzybylskiClinic of Cardiac Transplantation and Mechanical Circulatory Support, Department of Heart Diseases, Wroclaw Medical University, Wroclaw, Poland.
Piotr PodolecPulmonary Circulation Centre, Department of Cardiac and Vascular Diseases, Faculty of Medicine, Jagiellonian University Medical College, Centre for Rare Cardiovascular Diseases, John Paul II Hospital in Krakow, Krakow, Poland.
Dariusz ZielińskiDepartment of Cardiac Surgery, Medicover Hospital, Warsaw, Poland.
Andrzej BiedermanDepartment of Cardiac Surgery, Medicover Hospital, Warsaw, Poland.
Adam TorbickiDepartment of Pulmonary Circulation, Thromboembolic Diseases and Cardiology, European Health Centre Otwock, Centre of Postgraduate Medical Education, Warsaw, Poland.
Piotr PruszczykDepartment of Internal Medicine and Cardiology, Medical University of Warsaw, Warsaw, Poland.
Marcin KurzynaDepartment of Pulmonary Circulation, Thromboembolic Diseases and Cardiology, European Health Centre Otwock, Centre of Postgraduate Medical Education, Warsaw, Poland.
Medical University of Warsaw · PLPoznan University of Medical Sciences · PLJagiellonian University · PLŁukasiewicz Research Network – PORT Polish Center for Technology Development · PLMedical University of Silesia · PLPomeranian Medical University · PLMedical University of Lublin · PLWroclaw Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBalloon pulmonary angioplasty (BPA) is a promising therapy for patients with chronic thromboembolic pulmonary hypertension (CTEPH) who are ineligible for pulmonary endarterectomy.

aimsThe present study aimed to evaluate the safety and efficacy of BPA for CTEPH using the first multicentre registry of a single European country.

methodsData were obtained from the Database of Pulmonary Hypertension in the Polish Population (NCT03959748), a prospective, multicentre registry of adult and paediatric pulmonary arterial hypertension (PAH) and CTEPH, for a total of 236 patients with confirmed CTEPH (124 women; mean age 67 years) who underwent 1,056 BPA procedures at eight institutions in Poland.

resultsIn 156 patients who underwent follow-up assessments after a median of 5.9 (IQR: 3.0-8.0) months after final BPA, the mean pulmonary arterial pressure decreased from 45.1±10.7 to 30.2±10.2 mmHg (p<0.001) and pulmonary vascular resistance from 642±341 to 324±183 dynes (p<0.001), and the six-minute walking test (6MWT) improved from 341±129 to 423±136 m (p<0.001). Pulmonary injury related to the BPA procedure occurred in 6.4% of all sessions. Eighteen patients (7.6%) died during follow-up, including 4 (1.7%) who died within 30 days after BPA. Overall survival was 92.4% (95% confidence interval [CI]: 87.6%-94.9%) three years after the initial BPA procedure.

conclusionsThis multicentre registry confirmed significant improvement of haemodynamic, functional, and biochemical parameters after BPA. Complication rates were low and overall survival comparable to the results of another registry. Therefore, BPA may be an important therapeutic option in patients with CTEPH in Poland.

Indexed as

Angioplasty, BalloonHypertension, PulmonaryPulmonary EmbolismAdultAgedChildChronic DiseaseFemaleHumansProspective StudiesPulmonary ArteryRegistriesTreatment Outcome

Identifiers

PMID34219663
PMCPMC9725062
OpenAlexW3181735892

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.