Evidence map›Paper›PMID 34218857›Full record

ArticleMayo Clinic proceedings2021

Post-COVID-19 Syndrome (Long Haul Syndrome): Description of a Multidisciplinary Clinic at Mayo Clinic and Characteristics of the Initial Patient Cohort.

Greg Vanichkachorn, Richard Newcomb, Clayton T Cowl, M Hassan Murad, Laura Breeher, Sara Miller, Michael Trenary, Daniel Neveau, Steven Higgins

Abstract read
In one paragraph

Article in Mayo Clinic proceedings, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 118 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
118citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

118 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Predictors of Anxiety, Depression, and Stress in Long COVID: Systematic Review of Prevalence.International journal of environmental research and public health · 2025
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Returning to Work after the COVID-19 Pandemic Earthquake: A Systematic Review.International journal of environmental research and public health · 2022
    Pooled it
  8. Post-COVID-19 fatigue: A systematic review.Frontiers in psychiatry · 2022
    Pooled it
  9. Trial
  10. Human brain matters: Navigating the neuropathology of COVID-19.Brain pathology (Zurich, Switzerland) · 2026
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article

58 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Greg VanichkachornDivision of Preventive, Occupational, and Aerospace Medicine, Mayo Clinic, Rochester, MN. Electronic address: Vanichkachorn.greg@mayo.edu.
Richard NewcombDivision of Preventive, Occupational, and Aerospace Medicine, Mayo Clinic, Rochester, MN.
Clayton T CowlDivision of Preventive, Occupational, and Aerospace Medicine, Mayo Clinic, Rochester, MN.
M Hassan MuradDivision of Preventive, Occupational, and Aerospace Medicine, Mayo Clinic, Rochester, MN.
Laura BreeherDivision of Preventive, Occupational, and Aerospace Medicine, Mayo Clinic, Rochester, MN.
Sara MillerDivision of Preventive, Occupational, and Aerospace Medicine, Mayo Clinic, Rochester, MN.
Michael TrenaryDivision of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN.
Daniel NeveauDivision of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN.
Steven HigginsDivision of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe characteristics of a series of patients reporting prolonged symptoms after an infection with coronavirus disease 2019 (COVID-19). PATIENTS AND

methodsThis study describes the multidisciplinary COVID-19 Activity Rehabilitation Program, established at Mayo Clinic to evaluate and treat patients with post-COVID syndrome, and reports the clinical characteristics of the first 100 patients receiving evaluation and management during the timeframe of June 1, 2020, and December 31, 2020.

resultsThe cohort consisted of 100 patients (mean age, 45.4±14.2 years; 68% women; mean body mass index, 30.2 kg/m

conclusionMost of the patients did not have COVID-19-related symptoms that were severe enough to require hospitalization, were younger than 65 years, and were more likely to be female, and most had no preexisting comorbidities before severe acute respiratory syndrome coronavirus 2 infection. Symptoms including mood disorders, fatigue, and perceived cognitive impairment resulted in severe negative impacts on resumption of functional and occupational activities in patients experiencing prolonged effects.

Indexed as

Academic Medical CentersAdultCohort StudiesCOVID-19FemaleHumansMaleMiddle AgedMinnesotaPost-Acute COVID-19 Syndrome

Identifiers

PMID34218857
PMCPMC8112396

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.