Evidence map›Paper›PMID 34218388›Full record

ReviewJournal of assisted reproduction and genetics2021

Perspectives on the development and future of oocyte IVM in clinical practice.

Michel De Vos, Michaël Grynberg, Tuong M Ho, Ye Yuan, David F Albertini, Robert B Gilchrist

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of assisted reproduction and genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed, 2 pooled it
23.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 2 syntheses or guidelines pooled it, 160 citations in OpenAlex.

  1. Pooled it
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  16. Expression ofInternational journal of reproductive biomedicine · 2025
    Article
  17. A Comparative Analysis ofLife (Basel, Switzerland) · 2025
    Article
  18. Review
  19. Application of Autologous Platelet-Rich Plasma-Supplemented Medium PromotesInternational journal of fertility & sterility · 2025
    Article
  20. Article

19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 5 countries.

Michel De VosCentre for Reproductive Medicine, UZ Brussel, Brussels, Belgium.ORCID https://orcid.org/0000-0001-5019-5924
Michaël GrynbergDepartment of Reproductive Medicine and Fertility Preservation, Antoine Béclère University Hospital, Clamart, Clamart, France.
Tuong M HoIVFMD, My Duc Hospital, Ho Chi Minh City, Vietnam.ORCID https://orcid.org/0000-0003-3528-7358
Ye YuanColorado Center for Reproductive Medicine, Lone Tree, CO, 80124, USA.ORCID https://orcid.org/0000-0002-9995-2209
David F AlbertiniBedford Research Foundation, 124 South Road, Bedford, MA, 01730, USA.ORCID https://orcid.org/0000-0001-7182-833X
Robert B GilchristFertility & Research Centre, School of Women's and Children's Health, University of New South Wales Sydney, Sydney, NSW, Australia. r.gilchrist@unsw.edu.au.ORCID http://orcid.org/0000-0003-1611-7142
Bedford Research Foundation · USColorado Center for Reproductive Medicine · USSechenov University · RUUniversité Paris-Sud · FRUNSW Sydney · AUViet Duc Hospital · VN

Funding

City Fertility Global N/Acolorado center for reproductive medicine N/Afonds national de la recherche scientifique de belgique 30443682National Health and Medical Research Council APP1139763Open Philanthropy N/Avietnam national foundation for science and technology development FWO.106-YS.2017.02
6 · The paper itself

Abstract

Oocyte in vitro maturation (IVM) is an assisted reproductive technology designed to obtain mature oocytes following culture of immature cumulus-oocyte complexes collected from antral follicles. Although IVM has been practiced for decades and is no longer considered experimental, the uptake of IVM in clinical practice is currently limited. The purpose of this review is to ensure reproductive medicine professionals understand the appropriate use of IVM drawn from the best available evidence supporting its clinical potential and safety in selected patient groups. This group of scientists and fertility specialists, with expertise in IVM in the ART laboratory and/or clinic, explore here the development of IVM towards acquisition of a non-experimental status and, in addition, critically appraise the current and future role of IVM in human ART.

Indexed as

Reproductive Techniques, AssistedFemaleHumansIn Vitro Oocyte Maturation TechniquesMeiosisOocytesOogenesisOvarian FolliclePolycystic Ovary SyndromeFertility preservationIn vitro maturation (IVM)Onco-fertilityOocyte maturationPolycystic ovary syndrome (PCOS)

Identifiers

PMID34218388
PMCPMC8266966
OpenAlexW3182380636

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.