Observational studyEuropean journal of pediatrics2022
COVID-19 in pediatric patients undergoing chronic dialysis and kidney transplantation.
Observational study in European journal of pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 26 citations in OpenAlex.
- Pediatric Kidney Transplantation: A Systematic Review.Children (Basel, Switzerland) · 2026Review
- IPNA clinical practice recommendations on care of pediatric patients with pre-existing kidney disease during seasonal outbreak of COVID-19.Pediatric nephrology (Berlin, Germany) · 2025Review
- Humoral and cellular immunogenicity of a fourth dose BNT162b2 in children with chronic kidney diseases.Clinical kidney journal · 2025Article
- Sociodemographic Profile of Pediatric Hemodialysis during the COVID-19 Pandemic and Challenges for Sustainable Development.Revista brasileira de enfermagem · 2025Article
- COVID-19 disease among children and young adults enrolled in the North American Pediatric Renal Trials and Collaborative Studies registry.Pediatric nephrology (Berlin, Germany) · 2024Article
- Acute kidney injury in children with moderate-severe COVID-19 and multisystem inflammatory syndrome in children: a referral center experience.Pediatric nephrology (Berlin, Germany) · 2024Article
- Observational
- Humoral and cellular immune response to SARS-CoV-2 mRNA BNT162b2 vaccine in pediatric kidney transplant recipients compared with dialysis patients and healthy children.Pediatric nephrology (Berlin, Germany) · 2023Article
- Immunologic Response to SARS-CoV-2 Vaccination in Pediatric Kidney Transplant Recipients: A Systematic Review and Meta-Analysis.Vaccines · 2023Review
- COVID-19 in immunocompromised children and adolescents.Clinical and experimental pediatrics · 2023Article
- Management of pediatric dialysis and kidney transplant patients after natural or man-made disasters.Pediatric nephrology (Berlin, Germany) · 2023Review
- Considering a COVID-19 vaccine mandate for pediatric kidney transplant candidates.Pediatric nephrology (Berlin, Germany) · 2022Review
- Impact of the COVID-19 pandemic on the kidney community: lessons learned and future directions.Nature reviews. Nephrology · 2022Review
- Covid-19 in Egyptian hemodialysis and kidney transplant children: retrospective analysis of single center experience.Italian journal of pediatrics · 2022Article
- The impact of COVID-19 on the pediatric solid organ transplant population.Seminars in pediatric surgery · 2022Review
- Pediatric transplantation during the COVID-19 pandemic.World journal of transplantation · 2022Review
- Return to School and COVID-19 Vaccination for Pediatric Solid Organ Transplant Recipients in the United States: Expert Opinion for 2021-2022.Journal of the Pediatric Infectious Diseases Society · 2022Article
- SARS-CoV2 mRNA Vaccine-Specific B-, T- and Humoral Responses in Adolescents After Kidney Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2022Article
Corrections and comments
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Authors and funding
16 authors at 12 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The study aims to present the incidence of COVID-19 in pediatric patients undergoing renal replacement therapy (RRT) and to compare the severity and outcomes of the disease between the dialysis and kidney transplant (KTx) groups. This multicenter observational study was conducted between 1 April and 31 December 2020 in Istanbul. Members of the Istanbul branch of the Turkish Pediatric Nephrology Association were asked to report all confirmed cases of COVID-19 who were on RRT, as well as the number of prevalent RRT patients under the age of 20. A total of 46 confirmed cases of COVID-19 were reported from 12 centers, of which 17 were dialysis patients, and 29 were KTx recipients. Thus, the incidence rate of COVID-19 was 9.3% among dialysis patients and 9.2% among KTx recipients over a 9-month period in Istanbul. Twelve KTx recipients and three dialysis patients were asymptomatic (p = 0.12). Most of the symptomatic patients in both the dialysis and KTx groups had a mild respiratory illness. Only two patients, one in each group, experienced a severe disease course, and only one hemodialysis patient had a critical illness that required mechanical ventilation. In the entire cohort, one hemodialysis patient with multiple comorbidities died.Conclusion: While most cases are asymptomatic or have a mild disease course, pediatric patients undergoing dialysis and a kidney transplant are at increased risk for COVID-19. What is Known: • In adult population, both dialysis patients and kidney transplant recipients are at increased risk for severe illness of COVID-19 and have higher mortality rate. • Children with kidney transplantation are not at increased risk for COVID-19 and most have mild disease course. • Data on children on dialysis are scarce. What is New: • Pediatric patients undergoing dialysis and kidney transplantation have an increased risk for COVID-19. • Most patients undergoing renal replacement therapy either on dialysis or transplanted develop asymptomatic or mild COVID-19 disease with a favorable outcome.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.