Evidence map›Paper›PMID 34218311›Full record

ArticleWorld journal of surgery2021

Surgical Resection of Tumors Invading the Inferior Vena Cava at the Hepatic Vein and Thoracic Levels.

Justin Issard, Antonio Sa Cunha, Dominique Fabre, Delphine Mitilian, Sacha Mussot, Olaf Mercier, David Boulate, Elie Fadel

Abstract read
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In one paragraph

Article in World journal of surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Justin IssardDepartment of Thoracic and Vascular Surgery and Lung and Heart-Lung Transplantation, Marie Lannelongue Hospital, 133 avenue de la Résistance, 92350, Le Plessis Robinson, France.
Antonio Sa CunhaDepartment of Hepatobiliary Surgery, Paul Brousse Hospital, Villejuif, France.
Dominique FabreDepartment of Thoracic and Vascular Surgery and Lung and Heart-Lung Transplantation, Marie Lannelongue Hospital, 133 avenue de la Résistance, 92350, Le Plessis Robinson, France.
Delphine MitilianDepartment of Thoracic and Vascular Surgery and Lung and Heart-Lung Transplantation, Marie Lannelongue Hospital, 133 avenue de la Résistance, 92350, Le Plessis Robinson, France.
Sacha MussotDepartment of Thoracic and Vascular Surgery and Lung and Heart-Lung Transplantation, Marie Lannelongue Hospital, 133 avenue de la Résistance, 92350, Le Plessis Robinson, France.
Olaf MercierDepartment of Thoracic and Vascular Surgery and Lung and Heart-Lung Transplantation, Marie Lannelongue Hospital, 133 avenue de la Résistance, 92350, Le Plessis Robinson, France.
David Boulate *Department of Thoracic and Vascular Surgery and Lung and Heart-Lung Transplantation, Marie Lannelongue Hospital, 133 avenue de la Résistance, 92350, Le Plessis Robinson, France. d.boulate@ghpsj.fr.ORCID http://orcid.org/0000-0003-4757-4565
Elie Fadel *Department of Thoracic and Vascular Surgery and Lung and Heart-Lung Transplantation, Marie Lannelongue Hospital, 133 avenue de la Résistance, 92350, Le Plessis Robinson, France.
Hôpital Marie Lannelongue · FRHôpital Paul-Brousse · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOur aim was to describe the results of our program of surgical resection of tumors invading the inferior vena cava (IVC) at the hepatic and thoracic levels. We hypothesized that similar surgical outcomes may be obtained compared to tumor resection below the hepatic vein level if the liver function was preserved.

methodsWe performed a single-center retrospective study of 72 consecutive patients who underwent surgical resection from 1996 to 2019 for tumors invading the IVC. We compared two groups based on tumor location below (group I/II) or above (group III/IV) the inferior limit of hepatic veins.

resultsTumor histology was similarly distributed between groups. In group III/IV (n = 35), sterno-laparotomy was used in 83% of patients, cardiopulmonary bypass in 77%, and deep hypothermic circulatory arrest in 17%; 23% underwent liver resection. Corresponding proportions in group I/II were 3%, 0%, 0%, and 8%. In group III/IV, 4 patients required emergency resection. Mortality on day 30 was 17% (n = 6) in group III/IV and 0% in group I/II (P = 0.01). There was no liver failure among the 66 postoperative survivors and 5 out of 6 patients who died postoperatively presented a preoperative or postoperative liver failure (P < 0.001). Overall survival was not significantly different between groups with a median follow-up of 15.1 months. R0 resection was achieved in 66% of group I/II and 49% of group III/IV patients (P = 0.03).

conclusionSurgical resection of tumors invading the inferior vena cava at hepatic vein and thoracic levels should be reserved to carefully selected patients without preoperative liver failure to minimize postoperative mortality.

Indexed as

Hepatic VeinsLiver NeoplasmsHepatectomyHumansRetrospective StudiesVena Cava, Inferior

Identifiers

PMID34218311
OpenAlexW3178494955

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.