ArticleTropical animal health and production2021
Thermoregulatory, oxidative stress and lipid responses in prepartum ewes administered with L-carnosine during the hot-dry season.
Article in Tropical animal health and production, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 5 citations in OpenAlex.
- Preclinical evidence and therapeutic perspectives on carnosine for the treatment of neurodegenerative disorders.AIMS neuroscience · 2025Review
- Effects of dietary l-carnosine supplementation on the growth, intestinal microbiota, and serum metabolome of fattening lambs.Frontiers in veterinary science · 2024Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of the study was to investigate the effects of L-carnosine administration to prepartum ewes on oxidative status, lipid profile and thermoregulatory responses in the tropics during the hot-dry season. Twenty pregnant ewes were allotted each into two groups of treated and untreated ewes. The untreated ewes received orally 10 mL of water, while treated ewes were administered orally with L-carnosine (100 mg/kg) daily during the last 3 weeks of gestation. Blood samples were obtained during pre-gestation on day 0, gestation days 136 and 143 and after lambing. Dry-bulb temperatures (DBTs) of the pen were measured once per week at 06:00, 14:00 and 18:00 h as well as the thermoregulatory responses of the ewes. Birth weights of the lambs were determined 2-3 h postpartum. The DBT (37.33 ± 1.20 °C) and temperature-humidity index (85.24 ± 1.91) were above the thermoneutral zone. The results revealed no significant effect of L-carnosine on thermoregulatory responses of ewes and on the live-birth weight of their lambs. Malondialdehyde, 8-isoprostane and triglyceride concentrations were lower (P < 0.05) in treated ewes than in untreated ewes, but superoxide dismutase, catalase and glutathione peroxidase activities were higher (P < 0.05) in treated ewes compared to untreated ewes. In conclusion, L-carnosine reduced lipo-peroxidative products and augmented antioxidant enzyme activities in prepartum ewes under hot-dry conditions.
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