Evidence map›Paper›PMID 34217715›Full record

ReviewExperimental cell research2021

The regulation of animal behavior by cellular stress responses.

Neşem P Özbey, Maximilian A Thompson, Rebecca C Taylor

Open access · hybridAbstract readReview
In one paragraph

Review in Experimental cell research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Beyond fructolysis: ketohexokinase orchestrates ER proteostasis in nutrient-stressed hepatocytes.American journal of physiology. Gastrointestinal and liver physiology · 2025
    Article
  4. UPReLife · 2024
    Article
  5. A neural mScience China. Life sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Neşem P ÖzbeyNeurobiology Division, MRC Laboratory of Molecular Biology, Cambridge, CB2 0QH, United Kingdom.
Maximilian A ThompsonNeurobiology Division, MRC Laboratory of Molecular Biology, Cambridge, CB2 0QH, United Kingdom.
Rebecca C TaylorNeurobiology Division, MRC Laboratory of Molecular Biology, Cambridge, CB2 0QH, United Kingdom. Electronic address: rtaylor@mrc-lmb.cam.ac.uk.
MRC Laboratory of Molecular Biology · GB

Funding

Medical Research Council MC_UP_1201/7
6 · The paper itself

Abstract

Cellular stress responses exist to detect the effects of stress on cells, and to activate protective mechanisms that promote resilience. As well as acting at the cellular level, stress response pathways can also regulate whole organism responses to stress. One way in which animals facilitate their survival in stressful environments is through behavioral adaptation; this review considers the evidence that activation of cellular stress responses plays an important role in mediating the changes to behavior that promote organismal survival upon stress.

Indexed as

Adaptation, PhysiologicalAnimalsBehavior, AnimalEnvironmentHumansSignal TransductionStress, PhysiologicalUnfolded Protein ResponseBehaviorSignalingStress responseTranscription factorUPR

Identifiers

PMID34217715
PMCPMC8363813
OpenAlexW3180288828

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.