Evidence map›Paper›PMID 34217333›Full record

ArticleMolecular brain2021

Kdm3b haploinsufficiency impairs the consolidation of cerebellum-dependent motor memory in mice.

Yong Gyu Kim, Myeong Seong Bak, Ahbin Kim, Yujin Kim, Yun-Cheol Chae, Ye Lee Kim, Yang-Sook Chun, Joon-Yong An, Sang-Beom Seo, Sang Jeong Kim and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular brain, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. [A case report of Diets-Jongmans syndrome caused by aZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Yong Gyu Kim *Department of Physiology, Seoul National University College of Medicine, Seoul, 03080, Korea.
Myeong Seong Bak *Department of Physiology, Seoul National University College of Medicine, Seoul, 03080, Korea.
Ahbin Kim *Department of Physiology, Seoul National University College of Medicine, Seoul, 03080, Korea.
Yujin KimDepartment of Biosystems and Biomedical Sciences, College of Health Sciences, Korea University, Seoul, 02841, Korea.
Yun-Cheol ChaeDepartment of Life Science, College of Natural Science, Chung-Ang University, Seoul, 06974, Korea.
Ye Lee KimDepartment of Biomedical Sciences, Seoul National University College of Medicine, Seoul, 03080, Korea.
Yang-Sook ChunDepartment of Physiology, Seoul National University College of Medicine, Seoul, 03080, Korea.
Joon-Yong AnDepartment of Biosystems and Biomedical Sciences, College of Health Sciences, Korea University, Seoul, 02841, Korea.
Sang-Beom SeoDepartment of Life Science, College of Natural Science, Chung-Ang University, Seoul, 06974, Korea.
Sang Jeong KimDepartment of Physiology, Seoul National University College of Medicine, Seoul, 03080, Korea. Sangjkim@snu.ac.kr.
Yong-Seok LeeDepartment of Physiology, Seoul National University College of Medicine, Seoul, 03080, Korea. yongseok7@snu.ac.kr.ORCID 0000-0002-6217-9574
Seoul National University · KRChung-Ang University · KRKorea University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Histone modifications are a key mechanism underlying the epigenetic regulation of gene expression, which is critically involved in the consolidation of multiple forms of memory. However, the roles of histone modifications in cerebellum-dependent motor learning and memory are not well understood. To test whether changes in histone methylation are involved in cerebellar learning, we used heterozygous Kdm3b knockout (Kdm3b

Indexed as

AnimalsCerebellumGene Expression RegulationHaploinsufficiencyHistonesJumonji Domain-Containing Histone DemethylasesLysineMaleMemory ConsolidationMethylationMiceMice, Inbred C57BLMotor ActivityHistonesJumonji Domain-Containing Histone DemethylasesKdm3b protein, mouseLysineCerebellumHistone modificationKdm3bOptokinetic response (OKR)

Identifiers

PMID34217333
PMCPMC8254933
OpenAlexW3178814087

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.