Evidence map›Paper›PMID 34216996›Full record

Observational studyMultiple sclerosis and related disorders2021

Opinions, beliefs and knowledge of people with multiple sclerosis on COVID-19 pandemic and vaccine.

Joana Moniz Dionísio, Mariana Santos, Ana Martins Rodrigues, André Rêgo, Joana Vítor, Sofia Delgado, Rita Pinheiro, Pedro Neves, Carlos Figueiredo, José Bandeira Costa and 3 more

Abstract readObservational Study
In one paragraph

Observational study in Multiple sclerosis and related disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. COVID-19 vaccines and multiple sclerosis disease-modifying therapies.Multiple sclerosis and related disorders · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Joana Moniz DionísioNeurology Departments of the Hospital Prof. Doutor Fernando Fonseca. Electronic address: joana.dionisio@hff.min-saude.pt.
Mariana SantosNeurology Departments of the Hospital Prof. Doutor Fernando Fonseca.
Ana Martins RodriguesHospital Beatriz Ângelo.
André RêgoNeurology Departments of the Hospital Prof. Doutor Fernando Fonseca.
Joana VítorHospital Beatriz Ângelo.
Sofia DelgadoNeurology Departments of the Hospital Prof. Doutor Fernando Fonseca.
Rita PinheiroNeurology Departments of the Hospital Prof. Doutor Fernando Fonseca.
Pedro NevesNeurology Departments of the Hospital Prof. Doutor Fernando Fonseca.
Carlos FigueiredoNeurology Departments of the Hospital Prof. Doutor Fernando Fonseca.
José Bandeira CostaNeurology Departments of the Hospital Prof. Doutor Fernando Fonseca; Instituto Português de Oncologia Francisco Gentil - Lisbon, Portugal.
José ValeHospital Beatriz Ângelo.
Vasco SalgadoNeurology Departments of the Hospital Prof. Doutor Fernando Fonseca.
Ângela TimóteoHospital Beatriz Ângelo.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundConsidering the potential COVID-19 impact on pwMS health and the importance of vaccination for this population, we decided to assess: (a) pwMS' beliefs and knowledge on COVID-19 pandemic; (b) their acceptance towards COVID-19 vaccination and (c) pwMS' opinions on general vaccination.

methodsObservational study, based on a cross-sectional (10-20

results270 respondents completed the full survey (response rate 58.2%). pwMS greatest concern during the pandemic was an aggravation of MS, especially by patients older than 50 years old. Almost 40% of the patients older than 50 felt that the pandemic negatively affected their MS related medical assistance. Most patients believed they would recover from COVID-19 infection. More than half of the responders feared a MS aggravation if they got COVID-19; this was more pronounced in patients with progressive MS. About 12% of the participants did not want to be vaccinated and almost 40% was unsure. Regarding vaccines in general, almost a third of the participants feared their side effects or MS related complications.

conclusionHaving knowledge of pwMS' opinions on COVID-19 pandemic impact and vaccination is useful to better address these issues. Fears and expectations towards vaccination must be discussed with pwMS.

Indexed as

COVID-19Multiple SclerosisVaccinesCOVID-19 VaccinesCross-Sectional StudiesHumansMiddle AgedPandemicsSARS-CoV-2COVID-19 VaccinesVaccinesCOVID-19 pandemicmultiple sclerosisopinionsquestionnairevaccines

Identifiers

PMID34216996
PMCPMC8234267

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.