ReviewNeuroscience and biobehavioral reviews2021
Disentangling the influences of multiple thalamic nuclei on prefrontal cortex and cognitive control.
Review in Neuroscience and biobehavioral reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed.
- Reversible modulation of a deep white matter surgical target for depression with low-intensity focused ultrasound.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Trial
- Shedding Light on Interaction Between Neurological Symptoms and Psychiatric Episodes in Multiple Sclerosis: Novel Hypothesis and Therapeutic Avenues.Molecular neurobiology · 2026Review
- Thalamic reticular nucleus in the pathophysiology of schizophrenia.Neural regeneration research · 2026Article
- The Central Medial Thalamus Serves as a Critical Hub for Preserved Arousability During Dexmedetomidine Sedation.Neuroscience bulletin · 2026Article
- The prefrontal cortex across scales: laminar architecture, white-matter constraints, and distributed control in cognition.Brain structure & function · 2026Review
- Do white matter microstructural alterations associated with childhood maltreatment explain psychopathology in early adulthood?-a longitudinal neuroimaging study.European child & adolescent psychiatry · 2026Article
- Dynamic thalamocortical functional connectivity disruptions in Parkinson's disease with probable REM sleep behavior disorder.Scientific reports · 2026Article
- Advances in neuroimaging studies of thalamic abnormalities in children with attention deficit hyperactivity disorder.Psychoradiology · 2026Review
- Differential alterations of thalamic subregions in children and adolescents with attention deficit hyperactivity disorder and comorbid internalizing/externalizing disorders.BMC psychiatry · 2025Article
- Chewing modulates theta oscillation and functional connectivity of the frontocentral cortex in attention and working memory.Scientific reports · 2025Article
- Article
- The Cortical Structural Model Extends to Thalamocortical Connections.The European journal of neuroscience · 2025Article
- Percheron syndrome with memory impairment as chief manifestation: A case report.World journal of clinical cases · 2025Article
- The spatial extent of anatomical connections within the thalamus varies across the cortical hierarchy in humans and macaques.bioRxiv : the preprint server for biology · 2025Article
- The Impact of Childhood Maltreatment on Central Pain Processing in Individuals With Psychosis.Bipolar disorders · 2025Article
- Alterations of white matter connectivity in thalamic-frontal pathways associated with inflammation in premenstrual syndrome.Psychoradiology · 2025Article
- Thalamic Volumes and Functional Networks Linked With Self-Regulation Dysfunction in Major Depressive Disorder.CNS neuroscience & therapeutics · 2024Article
- Genetic Implication of Specific Glutamatergic Neurons of the Prefrontal Cortex in the Pathophysiology of Schizophrenia.Biological psychiatry global open science · 2024Article
- Synaptic plasticity in human thalamocortical assembloids.Cell reports · 2024Article
- Thalamocortical architectures for flexible cognition and efficient learning.Trends in cognitive sciences · 2024Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
The prefrontal cortex (PFC) has a complex relationship with the thalamus, involving many nuclei which occupy predominantly medial zones along its anterior-to-posterior extent. Thalamocortical neurons in most of these nuclei are modulated by the affective and cognitive signals which funnel through the basal ganglia. We review how PFC-connected thalamic nuclei likely contribute to all aspects of cognitive control: from the processing of information on internal states and goals, facilitating its interactions with mnemonic information and learned values of stimuli and actions, to their influence on high-level cognitive processes, attentional allocation and goal-directed behavior. This includes contributions to transformations such as rule-to-choice (parvocellular mediodorsal nucleus), value-to-choice (magnocellular mediodorsal nucleus), mnemonic-to-choice (anteromedial nucleus) and sensory-to-choice (medial pulvinar). Common mechanisms appear to be thalamic modulation of cortical gain and cortico-cortical functional connectivity. The anatomy also implies a unique role for medial PFC in modulating processing in thalamocortical circuits involving other orbital and lateral PFC regions. We further discuss how cortico-basal ganglia circuits may provide a mechanism through which PFC controls cortico-cortical functional connectivity.
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