ArticleJournal of clinical hypertension (Greenwich, Conn.)2021
Association between pubertal development and elevated blood pressure in children.
Article in Journal of clinical hypertension (Greenwich, Conn.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- The Relationship Between Children's Diet and Risk Factors for Cardiovascular Disease.Nutrients · 2026Pooled it
- Hydrocortisone administration in preterm infants is not associated with adverse cardiovascular outcomes in childhood.Pediatric research · 2026Trial
- Vascular health and exercise in females throughout the lifespan: Exploring puberty, pregnancy and menopause.Experimental physiology · 2026Review
- Article
- Obesity and risk of hypertension in preadolescent urban school children: insights from Pakistan.Journal of health, population, and nutrition · 2024Article
- Obesity and Risk of Hypertension in Preadolescent Urban School Children: Insights from a Developing Country.Research square · 2024Article
- Effects of Puberty on Blood Pressure Trajectories - Underlying Processes.Current hypertension reports · 2023Review
- Article
- Urinary epidermal growth factor reflects vascular health in boys with either obesity or type 1 diabetes. A role for renin, or beyond?PloS one · 2023Article
- Association between pubertal development and elevated blood pressure in children.Journal of clinical hypertension (Greenwich, Conn.) · 2021Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Blood pressure (BP) increased with age and height development, but little was known about the effect of pubertal development on blood pressure in children. A cross-sectional study was performed among 4146 children aged 7-12 years old in China. Pubertal development was assessed based on breast stages and testicular volume. The associations of pubertal development with BP levels and the rate of elevated blood pressure (EBP) were quantified using multiple linear and logistic regressions. We found that pubertal developmental level was positively correlated with BP, and children who experienced puberty onset and early pubertal timing had higher BP levels and prevalence of EBP. After adjusting for covariates, children experienced puberty onset had 3.84 and 2.24 mmHg increase in systolic blood pressure and diastolic blood pressure, and 70%, 53%, and 62% increased odds of EBP, ESBP, and EDBP, respectively, compared with those without puberty onset. Similar results were observed for children who had early pubertal timing. The change of BP in puberty is greater and the association between pubertal development and BP is stronger in girls than boys. These findings suggested that pubertal development could be an important independent factor and one critical period for the EBP progress. Monitoring and management of pubertal development are necessary particularly among girls.
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Registered trials
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