Evidence map›Paper›PMID 34216401›Full record

ReviewAdvanced materials (Deerfield Beach, Fla.)2021

Biocatalytic Nanomaterials: A New Pathway for Bacterial Disinfection.

Xin Fan, Fan Yang, Chuanxiong Nie, Lang Ma, Chong Cheng, Rainer Haag

Open access · hybridAbstract readReview
In one paragraph

Review in Advanced materials (Deerfield Beach, Fla.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
12.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 195 citations in OpenAlex.

  1. Electronic-State Programming of Ultrasmall CeOAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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  9. AuCu@CuOAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  10. Piezoelectric Biomaterial with Advanced Design for Tissue Infection Repair.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  11. Article
  12. Ultrafast synthesis of L-His-FeFrontiers in bioengineering and biotechnology · 2025
    Article
  13. Review
  14. Review
  15. Review
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  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Xin FanDepartment of Chemistry and Biochemistry, Freie Universität Berlin, Takustraße 3, 14195, Berlin, Germany.
Fan YangCollege of Polymer Science and Engineering, Department of Ultrasound, West China Hospital, Sichuan University, Yihuan Road No. 24, Chengdu, 610065, China.
Chuanxiong NieDepartment of Chemistry and Biochemistry, Freie Universität Berlin, Takustraße 3, 14195, Berlin, Germany.
Lang MaCollege of Polymer Science and Engineering, Department of Ultrasound, West China Hospital, Sichuan University, Yihuan Road No. 24, Chengdu, 610065, China.
Chong ChengCollege of Polymer Science and Engineering, Department of Ultrasound, West China Hospital, Sichuan University, Yihuan Road No. 24, Chengdu, 610065, China.ORCID https://orcid.org/0000-0002-6872-2240
Rainer HaagDepartment of Chemistry and Biochemistry, Freie Universität Berlin, Takustraße 3, 14195, Berlin, Germany.ORCID https://orcid.org/0000-0003-3840-162X
Freie Universität Berlin · DESichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinical treatment of pathogenic infection has emerged as a growing challenge in global public health. Such treatment is currently limited to antibiotics, but abuse of antibiotics have induced multidrug resistance and high fatality rates in anti-infection therapies. Thus, it is vital to develop alternative bactericidal agents to open novel disinfection pathways. Drawing inspiration from elements of the human immune system that show great potential for controlling pathogens or regulating cell apoptosis, the design of biocatalytic nanomaterials (BCNs) have provided unrivaled opportunities for future antibacterial therapies. More significantly, BCNs exhibit various superior properties to immune cells and natural enzymes, such as higher biocatalytic performance, extraordinary stability against harsh conditions, and scalable production. In this review, the most recent efforts toward developing BCN-based biomedical applications in combating bacterial infections are focused upon. BCNs' antibacterial mechanisms, the classification of BCNs, antibacterial activities that can be triggered or augmented by energy conversion, and the eradication of biofilms with BCNs are systematically introduced and discussed. The current challenges and prospects of BCNs for biocatalytic disinfection are also summarized. It is anticipated this review will provide new therapeutic insights into combating bacteria and biofilms and offer significant new inspiration for designing future biocatalytic nanomaterials.

Indexed as

AnimalsAnti-Bacterial AgentsBacteriaBiocatalysisBiofilmsBiomimetic MaterialsDisinfectionDrug DesignHumansHydrogen PeroxideNanostructuresPhotochemical ProcessesReactive Oxygen SpeciesSemiconductorsSignal TransductionAnti-Bacterial AgentsHydrogen PeroxideReactive Oxygen Speciesantibacterial therapiesbiocatalytic nanomaterialsmetal-organic frameworksnanomedicines and biomedical applicationsreactive oxygen species

Identifiers

PMID34216401
PMCPMC11468881
OpenAlexW3174167338

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.