Evidence map›Paper›PMID 34216157›Full record

ArticleThe European journal of neuroscience2021

Control of exploration, motor coordination and amphetamine sensitization by cannabinoid CB

Alipi V Bonm, Izaskun Elezgarai, Christina M Gremel, Katie Viray, Nigel S Bamford, Richard D Palmiter, Pedro Grandes, David M Lovinger, Nephi Stella

Open access · greenAbstract read
In one paragraph

Article in The European journal of neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Astroglial CBGlia · 2025
    Article
  3. Article
  4. Review
  5. Distinct mechanisms of CB1 and GABAThe Journal of physiology · 2023
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Alipi V BonmDepartment of Pharmacology, University of Washington School of Medicine, Seattle, WA, USA.
Izaskun ElezgaraiAchucarro Basque Center for Neuroscience, Science Park of the University of the Basque Country UPV/EHU, Leioa, Spain.
Christina M GremelLaboratory for Integrative Neuroscience, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
Katie VirayDepartment of Pharmacology, University of Washington School of Medicine, Seattle, WA, USA.
Nigel S BamfordDepartment of Pediatrics, Neurology and Cellular and Molecular Physiology, Yale University, New Haven, CT, USA.
Richard D PalmiterHoward Hughes Medical Institute and Department of Biochemistry, University of Washington School of Medicine, Seattle, WA, USA.
Pedro GrandesAchucarro Basque Center for Neuroscience, Science Park of the University of the Basque Country UPV/EHU, Leioa, Spain.
David M LovingerLaboratory for Integrative Neuroscience, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
Nephi StellaDepartment of Pharmacology, University of Washington School of Medicine, Seattle, WA, USA.ORCID 0000-0002-4780-8360
University of Washington · USNational Institutes of Health · USUniversity of the Basque Country · ESHoward Hughes Medical Institute · US

Funding

Corticostriatal mechanisms of action learning and habit formationZIAAA000416 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI LOVINGER, DAVID M · 2009 to 2025
$25.2M
Dependence induced dysfunction of decision-making circuits.R01AA026077 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Christina M. Gremel · 2017 to 2026
$3.8M
Dopamine-Induced Striatal Synaptic PlasticityR01NS060803 · NINDS · YALE UNIVERSITY · PI BAMFORD, NIGEL SIMON · 2007 to 2019
$3.4M
Role of ABHD6 in 2-AG SignalingR01DA026430 · NIDA · UNIVERSITY OF WASHINGTON · PI STELLA, NEPHI · 2009 to 2018
$3.4M
ABHD6 and amphetamine stimulated locomotionR21DA047626 · NIDA · UNIVERSITY OF WASHINGTON · PI STELLA, NEPHI, ZWEIFEL, LARRY S · 2019 to 2020
$409k
The role of the medium spiny neuron CB1 receptor subpopulation in amphetamine-indF30DA033747 · NIDA · UNIVERSITY OF WASHINGTON · PI NAYDENOV, ALIPI · 2012 to 2015
$136k
Intramural NIH HHS ZIA AA000416NIAAA NIH HHS R01 AA026077NIDA NIH HHS F30 DA033747NIDA NIH HHS R01 DA026430NIDA NIH HHS R21 DA047626NIH HHS AA026077NIH HHS DA026430NIH HHS DA047626NIH HHS NS060803NIH HHS ZIAAA000416NINDS NIH HHS R01 NS060803
6 · The paper itself

Abstract

Activation of cannabinoid 1 receptors (CB

Indexed as

AmphetamineCannabinoidsCorpus StriatumReceptor, Cannabinoid, CB1AnimalsMiceMice, KnockoutNeuronsAmphetamineCannabinoidsReceptor, Cannabinoid, CB1endocannabinoidgenetically modifiedglobus pallidusmouse linesubstantia nigra

Identifiers

PMID34216157
PMCPMC9377695
OpenAlexW3174778544

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.