ArticleThe ultrasound journal2021
Mean value of B-mode optic nerve sheath diameter as an indicator of increased intracranial pressure: a systematic review and meta-analysis.
Article in The ultrasound journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06057155 (Correlation Between Intracranial Pressure and Optic Nerve Sheath Diameter Measured With CLOSED Bundle in Patients With Acute Brain Injury), which is not on this map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Correlation Between Intracranial Pressure and Optic Nerve Sheath Diameter Measured With CLOSED Bundle in Patients With Acute Brain Injury: Multicenter Observational Study
Who cites it
22 citing papers in PubMed.
- [Small tidal volume hyperventilation relieves intraocular and intracranial pressure elevation in prone spinal surgery: a randomized controlled trial].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2024Trial
- Multimodal perioperative monitoring of intracranial pressure surrogates and cerebral oxygenation during laparoscopic surgery: implications for early cognitive outcomes.BMC anesthesiology · 2026Observational
- Dose-dependent reduction of optic nerve sheath diameter during graded lower body negative pressure in healthy adults of both sexes.Frontiers in network physiology · 2026Article
- Point-of-care ultrasonography for detecting raised intracranial pressure through optic nerve sheath diameter in non-traumatic headache patients.World journal of radiology · 2025Review
- Ultrasound-measured optic nerve sheath diameter as a non-invasive tool for screening elevated-pressure from normal-pressure hydrocephalus: a cross-sectional study.Neurosurgical review · 2025Article
- The Role of Ultrasonographic Assessment of Optic Nerve Sheath Diameter in Prediction of Sepsis-Associated Encephalopathy: Prospective Observational Study.Neurocritical care · 2025Observational
- Efficacy of a theoretical-practical course for the ultrasound measurement of the optic nerve diameter in different healthcare operators.The ultrasound journal · 2025Article
- Effects of dexmedetomidine and sevoflurane on optic nerve sheath diameter and postoperative nausea and vomiting in patients undergoing microvascular decompression: a retrospective cohort study.BMC anesthesiology · 2025Article
- Optic Nerve Sheath Diameter Estimation to Detect Increased Intracranial Pressure in Traumatic Brain Injury patients at a Level I Trauma Center in Eastern India.Korean journal of neurotrauma · 2025Article
- Deep learning based optic nerve sheath diameter characterization and structure quantification on transorbital ultrasound images.Frontiers in medicine · 2025Article
- Measuring optic nerve sheath diameter in children: a simple ultrasound protocol for ICP assessment.Frontiers in pediatrics · 2025Article
- Ultrasound-based radiomics and clinical factors-based nomogram for early intracranial hypertension detection in patients with decompressive craniotomy.Frontiers in medical technology · 2025Article
- The Effects of Antioxidant Cocktail on Ophthalmological Changes Induced by a 60-Day Head-Down Bed Rest in a Randomized Trial.Life (Basel, Switzerland) · 2024Article
- Bedside ultrasonographic evaluation of optic nerve sheath diameter for monitoring of intracranial pressure in traumatic brain injury patients: a cross sectional study in level II trauma care center in India.Acute and critical care · 2024Article
- Global traumatic brain injury intracranial pressure: from monitoring to surgical decision.Frontiers in neurology · 2024Review
- Diagnostic accuracy of optic nerve sheath diameter on ultrasound for the detection of increased intracranial pressure in patients with traumatic brain injury: A systematic review and meta‑analysis.Biomedical reports · 2023Article
- Comprehensive assessment of physiological responses in women during the ESA dry immersion VIVALDI microgravity simulation.Nature communications · 2023Article
- Evaluation of commercially available point-of-care ultrasound for automated optic nerve sheath measurement.The ultrasound journal · 2023Article
- Does prolonged prone position affect intracranial pressure? prospective observational study employing Optic nerve sheath diameter measurements.BMC anesthesiology · 2023Observational
- A prospective exploratory study to assess echocardiographic changes in patients with supratentorial tumors - Effect of craniotomy and tumor decompression.Surgical neurology international · 2023Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTimely diagnosis and treatment of increased intracranial pressure can decrease morbidity and prevent mortality. The present meta-analysis aims to determine the mean value of the ONSD measured in patients with various elevated ICP etiologies under different clinical settings, as well as comparing the value of ONSD between patients with and without elevated ICP.
methodsThis meta-analysis complied with the Preferred Reporting Items for Systematic Reviews and Meta-analysis Statement8. PubMed, Embase, and Cochrane Library were searched to identify ONSD measured by US for patients with increased ICP from establishment to October 2020.
resultsA total of 779 patients with elevated ICP among 22 studies were included in the present meta-analysis. Studies were published between 2003 and 2020. Eighteen were comparative (18/22, 81.8%), and four were single-armed study (4/22, 18.2%). Twenty were prospective studies (20/22, 90.9%). There was moderate-to-high heterogeneity based on the prediction ellipse area and variance logit of sensitivity and specificity.
conclusionsThe mean value of the ONSD among patients diagnosed with increased ICP was 5.82 mm (95% CI 5.58-6.06 mm). Variations were observed based on etiology of intracranial hypertension, clinical settings where ONSD was measured, and standards for diagnosing intracranial hypertension. The US-ONSD among patient with elevated ICP was significantly higher than the normal control. Although a cut-off value is not clearly determined, these mean values can be implemented to evaluate the sensitivity and specificity of US-ONSD in diagnosing intracranial hypertension in future studies.
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