Evidence map›Paper›PMID 34215933›Full record

Observational studySupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2021

Self-care, resilience, and caregiver burden in relatives of patients with advanced cancer: results from the eQuiPe study.

Janneke van Roij, Linda Brom, Dirkje Sommeijer, Lonneke van de Poll-Franse, Natasja Raijmakers, eQuiPe study group

Open access · hybridAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 55 citations in OpenAlex.

  1. Which resilience-related factors are important for anxiety, depression, and stress in cancer caregivers?Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  5. Caregiver contribution to patient self‑care and quality of life among informal carers of adult patients with inflammatory bowel disease: a cross‑sectional study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
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  16. Resilience and its association with caregiving and psychosocial factors among lung cancer caregivers in Vietnam.European journal of oncology nursing : the official journal of European Oncology Nursing Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Janneke van RoijResearch & Development, Netherlands Comprehensive Cancer Organization (IKNL), PO box 19079, 3501 DB, Utrecht, The Netherlands.ORCID http://orcid.org/0000-0003-0787-3018
Linda BromResearch & Development, Netherlands Comprehensive Cancer Organization (IKNL), PO box 19079, 3501 DB, Utrecht, The Netherlands.
Dirkje SommeijerDepartment of Medical Oncology, Amsterdam University Medical Center, Amsterdam, The Netherlands.
Lonneke van de Poll-FranseResearch & Development, Netherlands Comprehensive Cancer Organization (IKNL), PO box 19079, 3501 DB, Utrecht, The Netherlands.
Natasja RaijmakersResearch & Development, Netherlands Comprehensive Cancer Organization (IKNL), PO box 19079, 3501 DB, Utrecht, The Netherlands. n.raijmakers@iknl.nl.
eQuiPe study group
Tilburg University · NLFlevoziekenhuis · NLNederlandse Vereniging voor Kindergeneeskunde · NLNetherlands Comprehensive Cancer Organisation · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeRelatives are often involved in caregiving for patients with advanced cancer and carry a heavy burden. Self-care and resilience might be beneficial to enhance their wellbeing and burden-bearing capacity. This study assessed the engagement in self-care and resilience in relatives of patients with advanced cancer and its association with their caregiver burden.

methodsThis study analyzed baseline data of the eQuiPe study, a prospective longitudinal, multicenter, observational study on quality of care and life of patients with advanced cancer and their relatives in which self-care (Self-care Practices Scale), resilience (Connor-Davidson Resilience Scale), and caregiver burden (Zarit Burden Interview (ZBI)) of relatives were included. Their scores were compared with a gender- and age-matched normative population. Multivariable logistic regression analysis was performed to assess the association between self-care and resilience with caregiver burden.

resultsMost of the 746 relatives were the patient's partner (78%) and 54% reported to be an informal caregiver of the patient. The median hours of caregiving a week for all relatives was 15 and 11% experienced high caregiver burden (ZBI > 20). Relatives who reported a high caregiver burden engaged less often in self-care (OR = .87) and were less resilient (OR = .76) compared to relatives with low/medium caregiver burden. Relatives with high caregiver burden were younger (OR = .96), highly educated (OR = 2.08), often reported to be an informal caregiver of the patient (OR = 2.24), and were less well informed about the importance of self-care (OR = .39).

conclusionA significant number of relatives of patients with advanced cancer experienced high caregiver burden. As more self-care and resilience were associated with lower experienced caregiver burden, creating awareness of the beneficial potential of self-care is important. Future studies should illuminate the causal relation. TRIAL REGISTRATION NUMBER: NTR6584 (date of registration: 30 June 2017).

Indexed as

Caregiver BurdenNeoplasmsCaregiversCost of IllnessHumansProspective StudiesSelf CareAdvanced cancerCaregiver burdenPalliative careQuality of lifeResilience informal caregiversSelf-care

Identifiers

PMID34215933
PMCPMC8549961
OpenAlexW3175376921

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.