Evidence map›Paper›PMID 34215803›Full record

Observational studyScientific reports2021

Frequency, risk factors, and outcomes of hospital readmissions of COVID-19 patients.

Antonio Ramos-Martínez, Lina Marcela Parra-Ramírez, Ignacio Morrás, María Carnevali, Lorena Jiménez-Ibañez, Manuel Rubio-Rivas, Francisco Arnalich, José Luis Beato, Daniel Monge, Uxua Asín and 15 more

Abstract readObservational Study
In one paragraph

Observational study in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
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  6. Thrombotic and Hemorrhagic Incidences in Patients After Discharge from COVID-19 Infection: A Systematic Review and Meta-Analysis.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Pooled it
  7. Article
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  9. Risk model derivation and clinical outcomes in COVID-19 pneumonia patients discharged from the emergency department.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2025
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  13. Clinical Characteristics and Outcome of Readmitted Adult Patients With Acute COVID-19 Infection Within 30 Days of Their Hospital Discharge.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Antonio Ramos-MartínezInfectious Diseases Unit, Internal Medicine Department, Hospital Universitario Puerta de Hierro-Majadahonda UAM, IDIPHSA, Maestro Rodrigo 2, 28222, Majadahonda, Madrid, Spain. aramos220@gmail.com.
Lina Marcela Parra-RamírezPreventive Medicine Department, Hospital Universitario Puerta de Hierro-Majadahonda UAM, IDIPHSA, Maestro Rodrigo 2, 28222, Majadahonda, Madrid, Spain.
Ignacio MorrásInternal Medicine Department, Hospital Universitario Puerta de Hierro-Majadahonda UAM, IDIPHSA, Maestro Rodrigo 2, 28222, Majadahonda, Madrid, Spain.
María CarnevaliInternal Medicine Department, 12 de Octubre University Hospital, Av. de Córdoba, s/n, 28041, Madrid, Spain.
Lorena Jiménez-IbañezInternal Medicine Department, Gregorio Marañon University Hospital, Dr. Esquerdo, 46, 28007, Madrid, Spain.
Manuel Rubio-RivasInternal Medicine Department, Bellvitge University Hospital, Carrer de La Feixa Llarga, s/n, 08907, L'Hospitalet de Llobregat, Barcelona, Spain.
Francisco ArnalichInternal Medicine Department, La Paz University Hospital, Paseo de La Castellana, 261, 28046, Madrid, Spain.
José Luis BeatoInternal Medicine Department, Albacete University Hospital Complex, Hermanos Falco, 37, 02006, Albacete, Spain.
Daniel MongeInternal Medicine Department, Segovia Hospital Complex, Luis Erik Clavería Neurólogo s/n, 40002, Segovia, Spain.
Uxua AsínInternal Medicine Department, Miguel Servet Hospital, Paseo Isabel la Católica, 1-3, 50009, Zaragoza, Spain.
Carmen SuárezInternal Medicine Department, La Princesa University Hospital, Diego de León, 62, 28006, Madrid, Spain.
Santiago Jesús FreireInternal Medicine Department, A Coruña University Hospital, Xubias de Arriba, 84, 15006 A, Coruña, Spain.
Manuel Méndez-BailónInternal Medicine Department, San Carlos Clinical Hospital, Prof Martín Lagos, s/n, 28040, Madrid, Spain.
Isabel PeralesInternal Medicine Department, Infanta Sofía Hospital, Paseo de Europa, 34, 28703, San Sebastián de los Reyes, Madrid, Spain.
José Loureiro-AmigoInternal Medicine Department, Moisès Broggi Hospital, Carrer de Jacint Verdaguer, 90, 08970, Sant Joan Despí, Barcelona, Spain.
Ana Belén Gómez-BeldaInternal Medicine Department, Dr. Peset University Hospital, Av. de Gaspar Aguilar, 90, 46017, Valencia, Spain.
Paula María PesqueiraInternal Medicine Department, Santiago Clinical Hospital, Rúa da Choupana, s/n, 15706, Santiago de Compostela, A Coruña, Spain.
Ricardo Gómez-HuelgasInternal Medicine Department, Regional University Hospital of Málaga, Biomedical Research Institute of Málaga (IBIMA), University of Málaga (UMA), Av. de Carlos Haya, 84, 29010, Málaga, Spain.
Carmen MellaInternal Medicine Department, Hospital Architect Marcide-Novoa Santos, Rúa Pardo Bazán, s/n, 15404, Ferrol, A Coruña, Spain.
Luis Felipe Díez-GarcíaInternal Medicine Department, Torrecárdenas Hospital, Hermandad de Donantes de Sangre, s/n, 04009, Almería, Spain.
Joaquim Fernández-SolaInternal Medicine Department, Clinic Barcelona Hospital, Villarroel, 170, 08036, Barcelona, Spain.
Ruth González-FerrerInternal Medicine Department, Tajo Hospital, Av. Amazonas Central, s/n, 28300, Aranjuez, Madrid, Spain.
Marina ArozaInternal Medicine Department, Insular de Gran Canaria Hospital, Av. Marítima del Sur, s/n, 35016, Las Palmas de Gran Canaria, Las Palmas, Spain.
Juan Miguel Antón-SantosInternal Medicine Department, Infanta Cristina University Hospital, Av. 9 de Junio, 2, 28981, Parla, Madrid, Spain.
Carlos Lumbreras BermejoInternal Medicine Department, 12 de Octubre University Hospital, Av. de Córdoba, s/n, 28041, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To determine the proportion of patients with COVID-19 who were readmitted to the hospital and the most common causes and the factors associated with readmission. Multicenter nationwide cohort study in Spain. Patients included in the study were admitted to 147 hospitals from March 1 to April 30, 2020. Readmission was defined as a new hospital admission during the 30 days after discharge. Emergency department visits after discharge were not considered readmission. During the study period 8392 patients were admitted to hospitals participating in the SEMI-COVID-19 network. 298 patients (4.2%) out of 7137 patients were readmitted after being discharged. 1541 (17.7%) died during the index admission and 35 died during hospital readmission (11.7%, p = 0.007). The median time from discharge to readmission was 7 days (IQR 3-15 days). The most frequent causes of hospital readmission were worsening of previous pneumonia (54%), bacterial infection (13%), venous thromboembolism (5%), and heart failure (5%). Age [odds ratio (OR): 1.02; 95% confident interval (95% CI): 1.01-1.03], age-adjusted Charlson comorbidity index score (OR: 1.13; 95% CI: 1.06-1.21), chronic obstructive pulmonary disease (OR: 1.84; 95% CI: 1.26-2.69), asthma (OR: 1.52; 95% CI: 1.04-2.22), hemoglobin level at admission (OR: 0.92; 95% CI: 0.86-0.99), ground-glass opacification at admission (OR: 0.86; 95% CI:0.76-0.98) and glucocorticoid treatment (OR: 1.29; 95% CI: 1.00-1.66) were independently associated with hospital readmission. The rate of readmission after hospital discharge for COVID-19 was low. Advanced age and comorbidity were associated with increased risk of readmission.

Indexed as

Patient ReadmissionAgedAged, 80 and overAge FactorsCOVID-19FemaleHumansMaleMiddle AgedPatient DischargeRetrospective StudiesRisk FactorsSARS-CoV-2

Identifiers

PMID34215803
PMCPMC8253752

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.