Evidence map›Paper›PMID 34215700›Full record

ReviewPractical neurology2021

Progressive supranuclear palsy: diagnosis and management.

James B Rowe, Negin Holland, Timothy Rittman

Abstract readReview
In one paragraph

Review in Practical neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Deep transcranial magnetic stimulation in progressive supranuclear palsy: a randomized double-blind, cross-over study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Trial
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  13. Observational
  14. Article
  15. Review
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  17. Tongue strength in progressive supranuclear palsy.Parkinsonism & related disorders · 2025
    Article
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  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

James B RoweDepartment of Clinical Neurosciences, University of Cambridge, Cambridge, Cambridgeshire, UK james.rowe@mrc-cbu.cam.ac.uk.
Negin HollandDepartment of Clinical Neurosciences, University of Cambridge, Cambridge, Cambridgeshire, UK.
Timothy RittmanDepartment of Clinical Neurosciences, University of Cambridge, Cambridge, Cambridgeshire, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Treating patients with progressive supranuclear palsy (PSP) is both effective and rewarding. This review aims to share our experience in the proactive management of PSP, considering the patient, the family and the medical context in which the illness unfolds. There are many opportunities to assist your patients, ameliorate their symptoms, reduce their risks and harm, and guide them through the complex medical, social and legal minefield that characterises life with chronic neurological illness. We summarise the challenges of early diagnosis, consider PSP mimics and the role of investigations in excluding these, and discuss the available pharmacological and non-pharmacological treatment strategies to tackle the common and challenging symptoms of PSP. The best treatment will be patient centred and as part of a multidisciplinary team.

Indexed as

Supranuclear Palsy, ProgressiveDiagnosis, DifferentialHumanscognitiondementiamovement disorderssupranuclear palsy

Identifiers

PMID34215700
PMCPMC8461411

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.