Evidence map›Paper›PMID 34215251›Full record

ArticleBMC health services research2021

Making patient blood management the new norm(al) as experienced by implementors in diverse countries.

Axel Hofmann, Donat R Spahn, Anke-Peggy Holtorf, PBM Implementation Group

Registry-linked trialAbstract read
In one paragraph

Article in BMC health services research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06878105 (Evaluation of Fixed and Personal Assets for Patient Blood Management Implementation in CEE Countries in Practice), which is not on this map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06878105 recruitingnot on this mapstarted 2024, after this paper: background citation

Evaluation of Fixed and Personal Assets for Patient Blood Management Implementation in CEE Countries in Practice

TypeobservationalSponsorSemmelweis UniversityRan2024 to 2025Enrolled2,000ConditionsAnemia, CoagulopathyArmsData collection on interventions performs as per medical routine
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  11. 2024 EACTS/EACTAIC Guidelines on patient blood management in adult cardiac surgery in collaboration with EBCP.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2025
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  13. Impact of Shelf-Life Extension on Platelet Availability: Results from an Inventory Management Modeling Study.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Axel Hofmann *Institute of Anesthesiology, University and University Hospital of Zurich, Zurich, Switzerland.
Donat R Spahn *Institute of Anesthesiology, University and University Hospital of Zurich, Zurich, Switzerland.
Anke-Peggy Holtorf *Health Outcomes Strategies GmbH, Colmarerstrasse 58, CH4055, Basel, Switzerland. anke.holtorf@health-os.com.ORCID http://orcid.org/0000-0002-4638-5351
PBM Implementation Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatient blood management (PBM) describes a set of evidence-based practices to optimize medical and surgical patient outcomes by clinically managing and preserving a patient's own blood. This concepts aims to detect and treat anemia, minimize the risk for blood loss and the need for blood replacement for each patient through a coordinated multidisciplinary care process. In combination with blood loss, anemia is the main driver for transfusion and all three are independent risk factors for adverse outcomes including morbidity and mortality. Evidence demonstrates that PBM significantly improves outcomes and safety while reducing cost by macroeconomic magnitudes. Despite its huge potential to improve healthcare systems, PBM is not yet adopted broadly. The aim of this study is to analyze the collective experiences of a diverse group of PBM implementors across countries reflecting different healthcare contexts and to use these experiences to develop a guidance for initiating and orchestrating PBM implementation for stakeholders from diverse professional backgrounds.

methodsSemi-structured interviews were conducted with 1-4 PBM implementors from 12 countries in Asia, Latin America, Australia, Central and Eastern Europe, the Middle East, and Africa. Responses reflecting the drivers, barriers, measures, and stakeholders regarding the implementation of PBM were summarized per country and underwent qualitative content analysis. Clustering the resulting implementation measures by levels of intervention for PBM implementation informed a PBM implementation framework.

resultsA set of PBM implementation measures were extracted from the interviews with the implementors. Most of these measures relate to one of six levels of implementation including government, healthcare providers, funding, research, training/education, and patients/public. Essential cross-level measures are multi-stakeholder communication and collaboration.

conclusionThe implementation matrix resulting from this research helps to decompose the complexity of PBM implementation into concrete measures on each implementation level. It provides guidance for diverse stakeholders to design, initiate and develop strategies and plans to make PBM a national standard of care, thus closing current practice gaps and matching this unmet public health need.

Indexed as

Blood TransfusionAfricaAsiaAustraliaEurope, EasternHumansMiddle EastCulture changeImplementationPatient blood managementPatient outcomesPractice changeTransfusion

Identifiers

PMID34215251
PMCPMC8249439

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.