ArticleBMC neurology2021
The clinical and prognostic values of optic nerve sheath diameter and optic nerve sheath diameter/eyeball transverse diameter ratio in comatose patients with supratentorial lesions.
Article in BMC neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05918705 (Is the Ratio of Optic Nerve Sheath Diameter to Eyeball Transverse Diameter Correlated with the Prognosis of Sepsis Associated Encephalopathy in Critically Ill Patients), which is not on this map. Cited by 13 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Is the Ratio of Optic Nerve Sheath Diameter to Eyeball Transverse Diameter Correlated with the Prognosis of Sepsis Associated Encephalopathy in Critically Ill Patients
Who cites it
13 citing papers in PubMed, 21 citations in OpenAlex.
- Article
- Article
- Measuring optic nerve sheath diameter in children: a simple ultrasound protocol for ICP assessment.Frontiers in pediatrics · 2025Article
- The role of cerebral ptosis in assessing recovery and prognosis in traumatic brain injury: a case report.AME case reports · 2025Article
- Optic nerve sheath diameters in nontraumatic brain injury: A scoping review and role in the intensive care unit.World journal of critical care medicine · 2024Article
- Bedside ultrasonographic evaluation of optic nerve sheath diameter for monitoring of intracranial pressure in traumatic brain injury patients: a cross sectional study in level II trauma care center in India.Acute and critical care · 2024Article
- Optic nerve sheath diameter/eyeball transverse diameter ratio by ultrasound in prediction of increased intracranial pressure in children with viral encephalitis.Frontiers in pediatrics · 2024Article
- Optic nerve sheath diameter measurement for the paediatric patient with an acute deterioration in consciousness.The ultrasound journal · 2023Article
- Association between optic nerve sheath diameter/eyeball transverse diameter ratio and neurological outcomes in patients with aneurysmal subarachnoid hemorrhage.Journal of Korean Neurosurgical Society · 2023Article
- Prognostic values of optic nerve sheath diameter for comatose patients with acute stroke: An observational study.World journal of clinical cases · 2022Article
- The Prognostic Value of Optic Nerve Sheath Diameter/Eyeball Transverse Diameter Ratio in the Neurological Outcomes of Out-of-Hospital Cardiac Arrest Patients.Medicina (Kaunas, Lithuania) · 2022Article
- Optic nerve sheath diameter and optic nerve sheath diameter/eyeball transverse diameter ratio in prediction of malignant progression in ischemic stroke.Frontiers in neurology · 2022Article
- Ultrasound-derived Optic Nerve Sheath Diameter to Eyeball Transverse Diameter Ratio in the Diagnosis of Acute Meningitis in Adults.Annals of Indian Academy of NeurologyArticle
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe optic nerve sheath diameter (ONSD) and ONSD/eyeball transverse diameter (ETD) ratio have been proven to be correlated with intracranial pressure. This study aimed to evaluate the prognostic roles of ONSD and the ONSD/ETD ratio in comatose patients with supratentorial lesions and to determine the relationship of these two indices with the prognosis of such patients.
methodsA total of 54 comatose patients with supratentorial lesions and 50 healthy controls were retrospectively included in this study. ONSD and ETD were measured by unenhanced computed tomography (CT). The differences in ONSD and the ONSD/ETD ratio between the two groups were compared. The prognosis of comatose patients was scored using the Glasgow Outcome Scale (GOS) at the 3-month follow-up, and these patients were classified into good (GOS score ≥ 3) and poor (GOS score < 3) prognosis groups. The differences in ONSD and the ONSD/ETD ratio were compared between comatose patients with good prognoses and those with poor prognoses.
resultsThe ONSD and ONSD/ETD ratios in the comatose patients were 6.30 ± 0.60 mm and 0.27 ± 0.03, respectively, and both were significantly greater than those in the healthy controls (5.10 ± 0.47 mm, t = 11.426, P < 0.0001; 0.22 ± 0.02, t = 11.468, P < 0.0001; respectively). ONSD in patients with poor prognosis was significantly greater than that in patients with good prognosis (6.40 ± 0.56 vs. 6.03 ± 0.61 mm, t = 2.197, P = 0.032). The ONSD/ETD ratio in patients with poor prognosis was significantly greater than that in patients with good prognosis (0.28 ± 0.02 vs. 0.26 ± 0.03, t = 2.622, P = 0.011). The area under the receiver operating characteristic (ROC) curve, used to predict the prognosis of comatose patients, was 0.650 (95% confidence interval (CI): 0.486-0.815, P = 0.078) for ONSD and 0.711 (95% CI: 0.548-0.874, P = 0.014) for the ONSD/ETD ratio.
conclusionsThe ONSD and ONSD/ETD ratios were elevated in comatose patients. The ONSD/ETD ratio might be more valuable than ONSD in predicting the prognoses of comatose patients with supratentorial lesions.
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