Evidence map›Paper›PMID 34215208›Full record

ArticleBMC pregnancy and childbirth2021

Stillbirth as left truncation for early neonatal death in California, 1989-2015: a time-series study.

Tim A Bruckner, Samantha Gailey, Abhery Das, Alison Gemmill, Joan A Casey, Ralph Catalano, Gary M Shaw, Jennifer Zeitlin

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC pregnancy and childbirth, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. National Trends in Suicides and Male Twin Live Births in the US, 2003 to 2019: An Updated Test of Collective Optimism and Selection in Utero.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2023
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Tim A BrucknerProgram in Public Health & Center for Population, Inequality, and Policy, University of California Irvine, 653 E. Peltason Dr., Irvine, CA, 92697, USA.
Samantha GaileySchool of Social Ecology, University of California Irvine, 209 Social Ecology I, Irvine, CA, 92697, USA. sgailey@uci.edu.ORCID http://orcid.org/0000-0002-4654-1211
Abhery DasProgram in Public Health, University of California Irvine, 653 E. Peltason Dr., Irvine, CA, 92697, USA.
Alison GemmillPopulation, Family and Reproductive Health, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe St., Baltimore, MD, 21205, USA.
Joan A CaseyMailman School of Public Health, Columbia University, 722 W. 168th St., New York, NY, 10032, USA.
Ralph CatalanoSchool of Public Health, University of California Berkeley, Berkeley, CA, 94720, USA.
Gary M ShawSchool of Medicine, Stanford University, Stanford, CA, 94305, USA.
Jennifer ZeitlinUniversité de Paris, CRESS, Obstetrical, Perinatal and Pediatric Epidemiology Research Team, EPOPé, INSERM, INRA, F-75004, Paris, France.
University of California, Irvine · USColumbia University · USInserm · FRJohns Hopkins University · USStanford University · USUniversity of California, Berkeley · US

Funding

True Metal fac coreP30ES009089 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MATTHEW S PERZANOWSKI · 1998 to 2026
$44.7M
NCBDD CDC HHS U01 DD001226NIEHS NIH HHS P30 ES009089
6 · The paper itself

Abstract

backgroundSome scholars posit that attempts to avert stillbirth among extremely preterm gestations may result in a live birth but an early neonatal death. The literature, however, reports no empirical test of this potential form of left truncation. We examine whether annual cohorts delivered at extremely preterm gestational ages show an inverse correlation between their incidence of stillbirth and early neonatal death.

methodsWe retrieved live birth and infant death information from the California Linked Birth and Infant Death Cohort Files for years 1989 to 2015. We defined the extremely preterm period as delivery from 22 to < 28 weeks of gestation and early neonatal death as infant death at less than 7 days of life. We calculated proportions of stillbirth and early neonatal death separately by cohort year, race/ethnicity, and sex. Our correlational analysis controlled for well-documented declines in neonatal mortality over time.

resultsCalifornia reported 89,276 extremely preterm deliveries (live births and stillbirths) to Hispanic, non-Hispanic (NH) Black, and NH white mothers from 1989 to 2015. Findings indicate an inverse correlation between stillbirth and early neonatal death in the same cohort year (coefficient: -0.27, 95% CI of - 0.11; - 0.42). Results remain robust to alternative specifications and falsification tests.

conclusionsFindings support the notion that cohorts with an elevated risk of stillbirth also show a reduced risk of early neonatal death among extremely preterm deliveries. Results add to the evidence base that selection in utero may influence the survival characteristics of live-born cohorts.

Indexed as

Infant, Extremely PrematurePerinatal DeathBiasCaliforniaCohort StudiesEthnicityFemaleHumansInfant, NewbornInterrupted Time Series AnalysisLive BirthPerinatal MortalityPregnancyStillbirthLeft truncation BiasLive birthNeonatal deathStillbirth

Identifiers

PMID34215208
PMCPMC8252318
OpenAlexW3176254249

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.