Evidence map›Paper›PMID 34215205›Full record

ArticleBMC nephrology2021

Chronic kidney disease: prevalence and association with handgrip strength in a cross-sectional study.

Yang Cheng, Min Liu, Yu Liu, Haifeng Xu, Xiaotian Chen, Hui Zheng, Xiaojun Wu, Zhixiang Shen, Chong Shen

Open access · goldAbstract read
In one paragraph

Article in BMC nephrology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Global health inequalities of chronic kidney disease: a meta-analysis.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024
    Pooled it
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  8. Nutrition across the Entire Lifespan in CKD: From Childhood to Senescence.Clinical journal of the American Society of Nephrology : CJASN · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yang ChengCenter for Health Management, Geriatric Hospital of Nanjing Medical University, 65 Jiangsu Road, 21009, Nanjing, China.
Min LiuDepartment of Chronic Non-communicable Diseases Control, Center for Disease Control and Prevention of Jurong City, 212400, Jurong, China.
Yu LiuDepartment of Chronic Non-communicable Diseases Control, Center for Disease Control and Prevention of Jurong City, 212400, Jurong, China.
Haifeng XuDepartment of Chronic Non-communicable Diseases Control, Center for Disease Control and Prevention of Jurong City, 212400, Jurong, China.
Xiaotian ChenDepartment of Clinical Epidemiology, Children's Hospital of Fudan University, 201102, Shanghai, China.
Hui ZhengCenter for Health Management, Geriatric Hospital of Nanjing Medical University, 65 Jiangsu Road, 21009, Nanjing, China.
Xiaojun WuPeople's Hospital of Jurong City, 212400, Jurong, China.
Zhixiang ShenCenter for Health Management, Geriatric Hospital of Nanjing Medical University, 65 Jiangsu Road, 21009, Nanjing, China. 13913000003@126.com.
Chong ShenDepartment of Epidemiology, School of Public Health, Nanjing Medical University, 101 Longmian Avenue, 211166, Nanjing, China. sc100@126.com.
Nanjing Medical University · CNChildren's Hospital of Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPoor physical function is strongly associated with mortality and poor clinical outcomes in adults with chronic kidney disease (CKD). Handgrip strength (HGS) is an important index for physical function in the general population, and the association between HGS and CKD is worth investigating.

methodsFrom September to November 2015, we conducted a cross-sectional study consisting of 10,407 participants in Jurong City, China. Age-related and sex-specific HGS percentile curves were constructed using the GAMLSS method. In addition, logistic regression was applied to estimate the association between HGS and the presence of CKD with odds ratios (ORs) and 95 % confidence intervals (CIs).

resultsParticipants with low HGS tended to be older and were more likely to have CKD (8.73 %). Smoothed centile curves of HGS showed a similar shape in both sexes: participants peaked at approximately 20-35 years old and gradually decreased after the age of 50. In addition, independent of age and other factors, the decreased presence of CKD was significantly identified in individuals with moderate (OR: 0.64, 95 % CI: 0.49-0.83) and high HGS (OR: 0.37, 95 % CI: 0.23-0.58).

conclusionsWe concluded that HGS was significantly negatively associated with CKD in Chinese community-dwelling persons.

Indexed as

Hand StrengthPhysical Functional PerformanceAdolescentAdultAgedAged, 80 and overAge FactorsChinaCross-Sectional StudiesFemaleHumansIndependent LivingMaleMiddle AgedPrevalenceRenal Insufficiency, ChronicChinese community-dwelling personschronic kidney diseaseHandgrip strength

Identifiers

PMID34215205
PMCPMC8252238
OpenAlexW3175973862

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.