Evidence map›Paper›PMID 34214566›Full record

ArticleEnvironmental research2021

The association between ambient air pollutants and pancreatic cancer in the Multiethnic Cohort Study.

David Bogumil, Anna H Wu, Daniel Stram, Juan Yang, Chiu-Chen Tseng, Loïc Le Marchand, Jun Wu, Iona Cheng, Veronica Wendy Setiawan

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environmental research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Impact of Pollution on Cancer: A Systematic Review and Meta-Analysis with Focus on Air Pollution.International journal of environmental research and public health · 2026
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. The Multiethnic Cohort: A Resource for the Study of Genetic and Nongenetic Cancer Risk across Populations.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026
    Article
  6. Article
  7. Review
  8. Particulate matter increases bone morphogenetic protein 2 in lung fibroblasts.American journal of physiology. Lung cellular and molecular physiology · 2026
    Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Different Mortality Risks of Long-Term Exposure to Particulate Matter across Different Cancer Sites.International journal of environmental research and public health · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

David BogumilDepartment of Preventive Medicine, Keck School of Medicine of University of Southern California, Los Angeles, CA, USA.
Anna H WuDepartment of Preventive Medicine, Keck School of Medicine of University of Southern California, Los Angeles, CA, USA; Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA.
Daniel StramDepartment of Preventive Medicine, Keck School of Medicine of University of Southern California, Los Angeles, CA, USA.
Juan YangDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA.
Chiu-Chen TsengDepartment of Preventive Medicine, Keck School of Medicine of University of Southern California, Los Angeles, CA, USA.
Loïc Le MarchandEpidemiology Program, University of Hawaii Cancer Center, Honolulu, HI, USA.
Jun WuDepartment of Environmental and Occupational Health, Program in Public Health, Susan and Henry Samueli College of Health Sciences, University of California, Irvine, Irvine, CA, USA.
Iona ChengDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA.
Veronica Wendy SetiawanDepartment of Preventive Medicine, Keck School of Medicine of University of Southern California, Los Angeles, CA, USA; Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA; Department of Medicine, Keck School of Medicine of University of Southern California, Los Angeles, CA, USA. Electronic address: vsetiawa@usc.edu.
University of Southern California · USUniversity of California, San Francisco · USUniversity of California, Irvine · USUniversity of Hawaiʻi at Mānoa · US

Funding

Understanding Population Differences in Cancer: The MEC StudyU01CA164973 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI HAIMAN, CHRISTOPHER ALAN, LE MARCHAND, LOIC · 2015 to 2025
$37.4M
Multidisciplinary Training in Ethnic Diversity and Cancer DisparitiesT32CA229110 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI HAIMAN, CHRISTOPHER ALAN, LE MARCHAND, LOIC · 2019 to 2023
$2.1M
Investigating the cause of racial/ethnic disparity in pancreatic cancer incidenceR01CA209798 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI SETIAWAN, VERONICA WENDY · 2017 to 2020
$1.8M
NCI NIH HHS R01 CA209798NCI NIH HHS T32 CA229110NCI NIH HHS U01 CA164973
6 · The paper itself

Abstract

backgroundPrior studies examining the association between ambient air pollutants and pancreatic cancer have been conducted in racially/ethnically homogeneous samples and have produced mixed results, with some studies supporting evidence of an association with fine particulate matter.

methodsTo further investigate these findings, we estimated exposure levels of particulate matter (PM

resultsA total of 821 incident pancreatic cancer and 1,660,488 person-years accumulated over the study period, with an average follow-up time of over 16 years. PM

conclusionsOur findings support prior research identifying an association between fine particulate matter, PM

Indexed as

Air PollutantsAir PollutionPancreatic NeoplasmsCohort StudiesEnvironmental ExposureFemaleHumansIncidenceMaleParticulate MatterAir PollutantsParticulate MatterAir pollutionMultiethnicPancreatic cancerPM(2.5)

Identifiers

PMID34214566
PMCPMC8578294
OpenAlexW3175220932

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.