Evidence map›Paper›PMID 34214266›Full record

ArticleBiomedica : revista del Instituto Nacional de Salud2021

Seroprevalence of arboviruses in Ecuador: Implications for improved surveillance.

Ernesto Gutiérrez-Vera, Leandro Patiño, Martha Castillo-Segovia, Víctor Mora-Valencia, Julio Montesdeoca-Agurto, Mary Regato-Arrata

Erratum issuedOpen access · diamondAbstract read
In one paragraph

Article in Biomedica : revista del Instituto Nacional de Salud, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ernesto Gutiérrez-VeraDepartamento de Virología, Instituto Nacional de Investigación en Salud Pública "Dr. Leopoldo Izquieta Pérez", Guayaquil, Ecuador. biomedica@ins.gov.co.
Leandro PatiñoDepartamento de Virología, Instituto Nacional de Investigación en Salud Pública "Dr. Leopoldo Izquieta Pérez", Guayaquil, Ecuador; Dirección Técnica de Investigación, Desarrollo e Innovación, Instituto Nacional de Investigación en Salud Pública "Dr. Leopoldo Izquieta Pérez", Guayaquil, Ecuador. lpatino@inspi.gob.ec.
Martha Castillo-SegoviaDepartamento de Virología, Instituto Nacional de Investigación en Salud Pública "Dr. Leopoldo Izquieta Pérez", Guayaquil, Ecuador; Escuela de Medicina, Universidad de Especialidades Espíritu Santo, Samborondón, Ecuador. biomedica@ins.gov.co.
Víctor Mora-ValenciaDepartamento de Virología, Instituto Nacional de Investigación en Salud Pública "Dr. Leopoldo Izquieta Pérez", Guayaquil, Ecuador; Laboratorio Clínico, Hospital General Guasmo Sur, Guayaquil, Ecuador. biomedica@ins.gov.co.
Julio Montesdeoca-AgurtoDepartamento de Virología, Instituto Nacional de Investigación en Salud Pública "Dr. Leopoldo Izquieta Pérez", Guayaquil, Ecuado. biomedica@ins.gov.co.
Mary Regato-ArrataDepartamento de Virología, Instituto Nacional de Investigación en Salud Pública "Dr. Leopoldo Izquieta Pérez", Guayaquil, Ecuador; Centro de Referencia Nacional de Virus Exantemáticos, Gastroentéricos y Transmitidos por vectores, Instituto Nacional de Investigación en Salud Pública "Dr. Leopoldo Izquieta Pérez", Guayaquil, Ecuador. biomedica@ins.gov.co.
Instituto Nacional de Investigación en Salud Pública · EC

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionArthropod-borne viruses (arboviruses) cause morbidity and mortality in humans and domestic animals worldwide. The percentage of population immunity or susceptibility to these viruses in Ecuador is unknown.

objectivesTo investigate the proportion of Ecuadorian populations with IgG antibodies (Abs) (past exposure/immunity) and IgM Abs (current exposure) against flaviviruses and alphaviruses and to study the activity of these viruses in Ecuador. MATERIALS AND

methodsDuring 2009-2011, we conducted a serosurvey for selected arboviruses in humans (n=1,842), equines (n=149), and sentinel hamsters (n=84) at two coastal locations and one in the Amazon basin (Eastern Ecuador) using enzyme-linked immunosorbent assay and hemagglutination inhibition test.

resultsFrom 20.63% to 63.61% of humans showed IgG-antibodies for the flaviviruses: Dengue virus (DENV), yellow fever virus (YFV) Saint Louis encephalitis virus, and West Nile virus (WNV); from 4.67% to 8.63% showed IgG-Abs for the alphaviruses: Venezuelan equine encephalitis virus, eastern equine encephalitis virus, and western equine encephalitis virus. IgM-Abs were found for DENV and WNV. Equines and hamsters showed antibodies to alphaviruses in all locations; two hamsters seroconverted to YFV in the Amazonia.

conclusionsThe results show a YFV vaccination history and suggest the activity of arboviruses not included in the current surveillance scheme. Enhanced arbovirus and mosquito surveillance, as well as continued YFV vaccination and evaluation of its coverage/effectiveness, are recommended.

Indexed as

ArbovirusesWest Nile virusAnimalsAntibodies, ViralCricetinaeEcuadorHorsesHumansImmunoglobulin GImmunoglobulin MSeroepidemiologic StudiesAntibodies, ViralImmunoglobulin GImmunoglobulin MArbovirusdengue virusEastern equineencephalitis virusVenezuelan equineWest Nile virusyellow fever virus

Identifiers

PMID34214266
PMCPMC8382292
OpenAlexW3127403212

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.