Evidence map›Paper›PMID 34214261›Full record

ArticleBiomedica : revista del Instituto Nacional de Salud2021

Leptospirosis and rickettsiosis, a diagnostic challenge for febrile syndrome in endemic areas

René Ramírez-García, Juan Carlos Quintero, Aixa Paola Rosado, Margarita Arboleda, Víctor Alejandro González, Piedad Agudelo-Flórez

Abstract readCase Reports
In one paragraph

Article in Biomedica : revista del Instituto Nacional de Salud, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Serologically Confirmed Human Leptospirosis in Colombia, 2015-2020.The American journal of tropical medicine and hygiene · 2024
    Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

René Ramírez-GarcíaGrupo de Investigación en Ciencias Básicas, Escuela de Graduados, Universidad CES, Medellín, Colombia; Grupo de Investigación en Ciencias Veterinarias "Centauro", Facultad de Ciencias Agrarias, Universidad de Antioquia, Medellín, Colombia. renatogarnoss@gmail.com.
Juan Carlos QuinteroGrupo de Investigación en Ciencias Veterinarias Centauro, Facultad de Ciencias Agrarias, Universidad de Antioquia, Medellín, Colombia. biomedica@ins.gov.co.
Aixa Paola RosadoHospital Antonio Roldán Betancur, IPS Universitaria, Apartadó, Colombia. biomedica@ins.gov.co.
Margarita ArboledaGrupo de Investigación en Medicina Tropical, Instituto Colombiano de Medicina Tropical - ICMT-CES, Apartadó, Colombia. biomedica@ins.gov.co.
Víctor Alejandro GonzálezGrupo de Investigación en Ciencias Básicas, Escuela de Graduados, Universidad CES, Medellín, Colombia. biomedica@ins.gov.co.
Piedad Agudelo-FlórezGrupo de Investigación en Ciencias Básicas, Escuela de Graduados, Universidad CES, Medellín, Colombia. biomedica@ins.gov.co.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This is the case of a 50-year-old male from the region of Urabá, Colombia, with a mixed infection by Rickettsia rickettsii and Leptospira interrogans serovar Copenhageni ST78 and negative test for malaria and dengue fever. The patient presented with febrile syndrome and was unresponsive to systemic antibiotic treatment, who finally died in the intensive care unit. We established the postmortem diagnosis through molecular typification of the two etiological agents. In the inspection at the patient’s home, we found a Rattus rattus specimen infected with L. interrogans of the same serovar found in him. We found no ticks parasitizing the domestic animals cohabitating with the patient. This case of a mixed infection with progressive and fatal symptoms in a patient with occupational risk in a tropical disease endemic zone highlights the importance of considering the potential presentation of simultaneous etiologies in patients with multiple medical visits for unresolved febrile syndromes associated with risky exposure during agricultural activities.

Indexed as

CoinfectionLeptospirosisRickettsia InfectionsAnimalsAntibodies, BacterialHumansMaleMiddle AgedRatsRickettsia rickettsiiAntibodies, BacterialfeverhemorrhageLeptospirosis/diagnosisRickettsiaceae infections/diagnosiszoonosis

Identifiers

PMID34214261
PMCPMC8372841

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.