Evidence map›Paper›PMID 34214171›Full record

ArticleEndocrinology2021

Early Life Stress Affects the HPT Axis Response in a Sexually Dimorphic Manner.

Kristen R Vella, Anthony N Hollenberg

Abstract readComment
In one paragraph

Article in Endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Kristen R VellaDivision of Endocrinology, Diabetes and Metabolism, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, NY, USA.
Anthony N HollenbergDivision of Endocrinology, Diabetes and Metabolism, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, NY, USA.ORCID 0000-0002-3073-6188

Funding

COREPRESSOR REGULATION OF THYROID HORMONE ACTIONR01DK056123 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI HOLLENBERG, ANTHONY N · 2000 to 2023
$7.6M
Thyroid Follicular Cell Signaling and Development in HumansR01DK105029 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI ANTHONY N HOLLENBERG, Darrell N. Kotton · 2016 to 2026
$3.7M
Thyroid Hormone Signaling in Human HepatocytesR01DK117940 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI HOLLENBERG, ANTHONY N, WILSON, ANDREW A · 2019 to 2022
$2.7M
NIDDK NIH HHS R01 DK056123NIDDK NIH HHS R01 DK105029NIDDK NIH HHS R01 DK117940
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adverse Childhood ExperiencesHypothalamo-Hypophyseal SystemSex FactorsAnimalsFemaleHumansMaleThyroid GlandThyrotropin-Releasing HormoneThyrotropin-Releasing Hormonegene methylationHPT axisthyroid hormoneTRH

Identifiers

PMID34214171
PMCPMC8315292

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.