Evidence map›Paper›PMID 34213888›Full record

ArticleAnalytical chemistry2021

DNA-Based Nanoswitches: Insights into Electrochemiluminescence Signal Enhancement.

Alessandra Zanut, Marianna Rossetti, Massimo Marcaccio, Francesco Ricci, Francesco Paolucci, Alessandro Porchetta, Giovanni Valenti

Open access · hybridAbstract read
In one paragraph

Article in Analytical chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Alessandra ZanutDepartment of Chemistry "G. Ciamician", University of Bologna, Via Selmi 2, 40126 Bologna, Italy.
Marianna RossettiDipartimento di Scienze e Tecnologie Chimiche, University of Rome, Tor Vergata, Via della Ricerca Scientifica, 00133 Rome, Italy.
Massimo MarcaccioDepartment of Chemistry "G. Ciamician", University of Bologna, Via Selmi 2, 40126 Bologna, Italy.ORCID 0000-0001-9032-0742
Francesco RicciDipartimento di Scienze e Tecnologie Chimiche, University of Rome, Tor Vergata, Via della Ricerca Scientifica, 00133 Rome, Italy.ORCID 0000-0003-4941-8646
Francesco PaolucciDepartment of Chemistry "G. Ciamician", University of Bologna, Via Selmi 2, 40126 Bologna, Italy.ORCID 0000-0003-4614-8740
Alessandro PorchettaDipartimento di Scienze e Tecnologie Chimiche, University of Rome, Tor Vergata, Via della Ricerca Scientifica, 00133 Rome, Italy.ORCID 0000-0002-4061-5574
Giovanni ValentiDepartment of Chemistry "G. Ciamician", University of Bologna, Via Selmi 2, 40126 Bologna, Italy.ORCID 0000-0002-6223-2072
University of Bologna · ITUniversity of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Electrochemiluminescence (ECL) is a powerful transduction technique that has rapidly gained importance as a powerful analytical technique. Since ECL is a surface-confined process, a comprehensive understanding of the generation of ECL signal at a nanometric distance from the electrode could lead to several highly promising applications. In this work, we explored the mechanism underlying ECL signal generation on the nanoscale using luminophore-reporter-modified DNA-based nanoswitches (i.e., molecular beacon) with different stem stabilities. ECL is generated according to the "oxidative-reduction" strategy using

Indexed as

DNALuminescent MeasurementsElectrodesPhotometryDNA

Identifiers

PMID34213888
PMCPMC8382220
OpenAlexW3174848725

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.