Evidence map›Paper›PMID 34213771›Full record

ArticleInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2021

COVID-19-related deaths among women of reproductive age in Brazil: The burden of postpartum.

Roxana Knobel, Maíra L S Takemoto, Marcos Nakamura-Pereira, Mariane O Menezes, Vicente K Borges, Leila Katz, Melania M R Amorim, Carla B Andreucci

Open access · bronzeAbstract read
In one paragraph

Article in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Five years after the COVID-19 pandemic began: lessons on vaccination and obstetric care in Brazil.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. COVID-19 disease and vaccination in pregnant and lactating women.American journal of reproductive immunology (New York, N.Y. : 1989) · 2022
    Review
  7. COVID-19 and Pregnancy.Infectious disease clinics of North America · 2022
    Review
  8. Review
  9. Article
  10. COVID-19-related deaths among women of reproductive age in Brazil: The burden of postpartum.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Roxana KnobelDepartment of Gynecology and Obstetrics, Federal University of Santa Catarina (UFSC, Florianopolis, Santa Catarina, Brazil.
Maíra L S TakemotoSão Paulo State University (UNESP, Medical School of Botucatu, Botucatu, São Paulo, Brazil.
Marcos Nakamura-PereiraNational Institute for Women, Children and Adolescents Health Fernandes Figueira, Oswaldo Cruz Foundation, Rio de Janeiro, RJ, Brazil.
Mariane O MenezesSão Paulo State University (UNESP, Medical School of Botucatu, Botucatu, São Paulo, Brazil.
Vicente K BorgesDepartment of Automation and Systems, Control and Automation Engineering Program, Federal University of Santa Catarina (UFSC, Florianopolis, Santa Catarina, Brazil.
Leila KatzProfessor Fernando Figueira Institute of Integral Medicine (IMIP, Recife, PE, Brazil.
Melania M R AmorimProfessor Fernando Figueira Institute of Integral Medicine (IMIP, Recife, PE, Brazil.
Carla B AndreucciDepartment of Medicine, Federal University of Sao Carlos (UFSCAR, Sao Carlos, SP, Brazil.
Instituto de Medicina Integral Professor Fernando Figueira · BRUniversidade Estadual Paulista (Unesp) · BRUniversidade Federal de Santa Catarina · BRFundação Oswaldo Cruz · BRUniversidade Federal de São Carlos · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare risk of death due to COVID-19 among pregnant, postpartum, and non-pregnant women of reproductive age in Brazil, using the severe acute respiratory syndrome surveillance system (SARS-SS).

methodsA secondary analysis was performed of the Brazilian official SARS-SS, with data retrieved up to August 17, 2020. Cases were stratified by pregnancy status, risk factors or co-morbidities, and outcome (death or recovery). Multiple logistic regression was employed to examine associations between independent variables and risk of death.

resultsA total of 24 805 cases were included, with 3129 deaths (12.6%), including 271 maternal deaths. Postpartum was associated with increased risk of death, admission to the intensive care unit (ICU), and mechanical ventilation. Co-morbidities with higher impact on case fatality rate among non-obstetric cases were cancer and neurological and kidney diseases. Among pregnant women, cancer, diabetes mellitus, obesity, and rheumatology diseases were associated with risk of death. In the postpartum subgroup, age over 35 years and diabetes mellitus were independently associated with higher chance of death.

conclusionPostpartum was associated with worse outcomes among the obstetric population, despite lower risk of dying without accessing ICU care. Non-pregnant women with cancer, neurological diseases, and kidney diseases have a higher risk of death due to COVID-19.

Indexed as

COVID-19Pregnancy Complications, InfectiousAdultBrazilFemaleHumansPostpartum PeriodPregnancySARS-CoV-2cardiovascular diseaseCOVID-19maternal deathobesitypostpartumpregnancywomen of reproductive age

Identifiers

PMID34213771
PMCPMC9087613
OpenAlexW3173237608

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.