Evidence map›Paper›PMID 34213618›Full record

ArticleCurrent microbiology2021

In Vitro Antidiabetic, Antioxidant Activity, and Probiotic Activities of Lactiplantibacillus plantarum and Lacticaseibacillus paracasei Strains.

GaYeong Won, Soo-Im Choi, NaYeong Park, Ji-Eun Kim, Chang-Ho Kang, Gun-Hee Kim

Open access · hybridAbstract read
In one paragraph

Article in Current microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 66 citations in OpenAlex.

  1. Article
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  9. A Combined Probiotic-International journal of molecular sciences · 2026
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  10. Review
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  12. Article
  13. Frontiers in microbiology · 2026
    Article
  14. Article
  15. Screening, characterization, and potential anti-hangover ability of selenium nanoparticle-enriched lactobacillus.International microbiology : the official journal of the Spanish Society for Microbiology · 2025
    Article
  16. Nutrients · 2025
    Article
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

GaYeong WonDepartment of Health Functional New Materials, Duksung Women's University, Seoul, 01369, Korea.ORCID http://orcid.org/0000-0002-0694-6345
Soo-Im ChoiDepartment of Health Functional New Materials, Duksung Women's University, Seoul, 01369, Korea.ORCID http://orcid.org/0000-0002-8362-3523
NaYeong ParkDepartment of Health Functional New Materials, Duksung Women's University, Seoul, 01369, Korea.ORCID http://orcid.org/0000-0003-0505-8159
Ji-Eun KimMEDIOGEN, Co., Ltd., Jecheon, 27159, Korea.ORCID http://orcid.org/0000-0003-1513-0804
Chang-Ho KangMEDIOGEN, Co., Ltd., Jecheon, 27159, Korea.ORCID http://orcid.org/0000-0001-6466-8550
Gun-Hee KimDepartment of Food and Nutrition, Duksung Women's University, Seoul, 01369, Korea. ghkim@duksung.ac.kr.ORCID http://orcid.org/0000-0001-8196-7149
Duksung Women's University · KRInsilicogen (South Korea) · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes, a chronic metabolic disorder, is characterized by persistent hyperglycemia. This study aimed to evaluate the hypoglycemic and antioxidant activities of lactic acid bacteria strains isolated from humans and food products and investigate the probiotic properties of the selected four strains. The hypoglycemic activity of the isolated strains was examined by evaluating the α-glucosidase and α-amylase inhibitory activities. The antioxidant activity was measured using the DPPH, ABTS, and FRAP assays. Four strains (Lactiplantibacillus plantarum MG4229, MG4296, MG5025, and Lacticaseibacillus paracasei MG5012) exhibited potent α-glucosidase inhibitory (>75%) and α-amylase inhibitory (>85%) activities, which were comparable to those of acarbose (>50%; 1000 μg/mL). Similarly, the radical scavenging and antioxidant activities of the four strains were comparable to those of ascorbic acid (50 μg/mL). Additionally, the probiotic properties of the four selected strains were examined based on acid and bile salt tolerance, auto-aggregation ability, and antibiotic resistance. The four strains were resistant to pH 2 (>50% of survivability) and 0.5% bile salt (>80% of survivability). Therefore, we suggest that the selected strains with hypoglycemic, antioxidant, probiotic properties can potentially prevent diabetes.

Indexed as

LactobacillalesProbioticsalpha-AmylasesAntioxidantsHumansHypoglycemic Agentsalpha-AmylasesAntioxidantsHypoglycemic Agents

Identifiers

PMID34213618
PMCPMC8289794
OpenAlexW3175142825

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.