Evidence map›Paper›PMID 34213615›Full record

ArticleCurrent microbiology2021

Molecular Identification and Antimicrobial Activity of Foliar Endophytic Fungi on the Brazilian Pepper Tree (Schinus terebinthifolius) Reveal New Species of Diaporthe.

Germana D Dos Santos, Renata R Gomes, Rosana Gonçalves, Gheniffer Fornari, Beatriz H L N S Maia, Claudia Schmidt-Dannert, Francois Gaascht, Chirlei Glienke, Gabriela X Schneider, Israella R Colombo and 4 more

Abstract read
PubMed Publisher
In one paragraph

Article in Current microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Insights into diversity and L-asparaginase activity of fungal endophytes associated with medicinal plant Grewia hirsuta.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
    Article
  7. Review
  8. Article
  9. Frontiers in microbiology · 2023
    Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Germana D Dos SantosMicrobiology, Parasitology and Pathology Post-Graduation Program, Basic Pathology Department, Federal University of Paraná State, Curitiba, 81531-980, Brazil.
Renata R GomesMicrobiology, Parasitology and Pathology Post-Graduation Program, Basic Pathology Department, Federal University of Paraná State, Curitiba, 81531-980, Brazil. rrgrenata@gmail.com.
Rosana GonçalvesUndergraduate Student in Biomedicine, Federal University of Paraná, Curitiba, PR, Brazil.
Gheniffer FornariMicrobiology, Parasitology and Pathology Post-Graduation Program, Basic Pathology Department, Federal University of Paraná State, Curitiba, 81531-980, Brazil.
Beatriz H L N S MaiaDepartment of Chemistry, Federal University of Paraná State, Curitiba, PR, Brazil.
Claudia Schmidt-DannertDepartment of Biochemistry, Molecular Biology & Biophysics, University of Minnesota, 140 Gortner Laboratory, 1479 Gortner Avenue, Saint Paul, MN, 55108, USA.
Francois GaaschtDepartment of Biochemistry, Molecular Biology & Biophysics, University of Minnesota, 140 Gortner Laboratory, 1479 Gortner Avenue, Saint Paul, MN, 55108, USA.
Chirlei GlienkeMicrobiology, Parasitology and Pathology Post-Graduation Program, Basic Pathology Department, Federal University of Paraná State, Curitiba, 81531-980, Brazil.
Gabriela X SchneiderMicrobiology, Parasitology and Pathology Post-Graduation Program, Basic Pathology Department, Federal University of Paraná State, Curitiba, 81531-980, Brazil.
Israella R ColomboUndergraduate Student in Biomedicine, Federal University of Paraná, Curitiba, PR, Brazil.
Juliana Degenhardt-GoldbachBrazilian Agricultural Research Corporation (EMBRAPA) Forestry, Colombo, PR, Brazil.
João L M PietschMicrobiology, Parasitology and Pathology Post-Graduation Program, Basic Pathology Department, Federal University of Paraná State, Curitiba, 81531-980, Brazil.
Magda C V Costa-RibeiroMicrobiology, Parasitology and Pathology Post-Graduation Program, Basic Pathology Department, Federal University of Paraná State, Curitiba, 81531-980, Brazil.
Vania A VicenteMicrobiology, Parasitology and Pathology Post-Graduation Program, Basic Pathology Department, Federal University of Paraná State, Curitiba, 81531-980, Brazil. vicente@ufpr.br.

Funding

capes 8887.311835/2018-00-AUXPE-2796/2018CNPq 30 7547/2012-4
6 · The paper itself

Abstract

The presence of endophytes promotes the biosynthesis of secondary plant metabolites. In this study, endophytic fungi were isolated from Schinus terebinthifolius to investigate their diversity and antimicrobial activity. A total of 272 endophytic fungi was obtained. These belonged to nine different genera: Alternaria, Colletotrichum, Diaporthe, Epicoccum, Fusarium, Pestalotiopsis, Phyllosticta, Xylaria, and Cryptococcus. Notably, Diaporthe foliorum was introduced as a new species, with accompanying morphological descriptions, illustrations, and a multigene phylogenetic analysis (using ITS, TEF1, TUB, HIS, and CAL). Among the 26 fungal morphotypes evaluated for antimicrobial activity, five strains had inhibitory effects against pathogenic microorganisms. Xylaria allantoidea CMRP1424 extracts showed antimicrobial activity against Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus. Diaporthe terebinthifolii CMRP1430 and CMRP1436 showed antimicrobial activity against E. coli, P. aeruginosa, S. aureus, and C. albicans. Meanwhile, D. foliorum CMRP1321 and D. malorum CMRP1438 extracts inhibited C. albicans alone. Three classes of chemical compounds were identified in D. foliorum CMRP1438 extracts: ferric chloride, potassium hydroxide, and vanillin-sulfuric acid. In conclusion, the endophytic isolates were able to produce bioactive agents with pharmaceutical potential as antibacterial and antifungal agents. As such, they may provide fresh leads in the search for new, biological sources of drug therapies.

Indexed as

AnacardiaceaeAnti-Infective AgentsAscomycotaEndophytesEscherichia coliFungiMicrobial Sensitivity TestsPhylogenyStaphylococcus aureusAnti-Infective Agents

Identifiers

PMID34213615

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.