Evidence map›Paper›PMID 34213427›Full record

ArticleEndoscopic ultrasound

Diagnostic utility of EUS-guided tissue acquisition in children: A tertiary care center experience.

Zaheer Nabi, Sundeep Lakhtakia, Radhika Chavan, Shujaath Asif, Jahangeer Basha, Rajesh Gupta, Raghavendra Yarlagadda, Palle Manohar Reddy, Rakesh Kalapala, D Nageshwar Reddy

Open access · greenAbstract read
In one paragraph

Article in Endoscopic ultrasound. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. EUS in pediatric patients.Endoscopic ultrasound
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Zaheer NabiDepartment of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, Telangana, India.
Sundeep LakhtakiaDepartment of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, Telangana, India.
Radhika ChavanDepartment of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, Telangana, India.
Shujaath AsifDepartment of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, Telangana, India.
Jahangeer BashaDepartment of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, Telangana, India.
Rajesh GuptaDepartment of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, Telangana, India.
Raghavendra YarlagaddaDepartment of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, Telangana, India.
Palle Manohar ReddyDepartment of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, Telangana, India.
Rakesh KalapalaDepartment of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, Telangana, India.
D Nageshwar ReddyDepartment of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, Telangana, India.
Asian Institute of Gastroenterology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesEUS is frequently utilized for tissue acquisition in adult patients. However, the literature is limited regarding the utility of EUS-guided fine-needle aspiration or biopsy (FNA or FNB) in children. In this study, we aim to evaluate the feasibility, safety, and diagnostic utility of EUS-FNA/FNB in children with various gastrointestinal diseases.

methodsThe data of children (≤18 years) who underwent EUS-FNA/FNB from March 2014 to June 2020 were analyzed, retrospectively. The following parameters were analyzed: technical success, adverse events, and impact on the final diagnosis.

resultsSixty-seven children (32 - boys, 14.8 ± 2.9 years, range 8-18 years), underwent EUS-guided tissue acquisition procedures using standard therapeutic echoendoscope during the study period. The indications included solid pancreatic lesions in 29 (43.3%), mediastinal or abdominal lymphadenopathy in 30 (44.7%), cystic pancreatic lesions in 5 (7.5%), subepithelial lesions in 2 (3%), and retroperitoneal mass in 1 (1.5%). EUS-FNA and-FNB were performed in 42 and 25 children, respectively. All the procedures could be successfully performed and there was no major procedure-related adverse event. Minor adverse events included self-limiting throat pain (10) and abdominal pain (3), self-limited bleeding at puncture site (3), and transient fever (1). EUS-FNA/FNB provided a histopathological diagnosis in 59 (88.1%) children.

conclusionEUS-guided tissue acquisition using standard echoendoscope is feasible and safe in the pediatric age group. EUS-FNA/FNB establishes diagnosis in majority of the children when performed for appropriate clinical indication.

Indexed as

EUSfine-needle aspirationfine-needle biopsy

Identifiers

PMID34213427
PMCPMC8411558
OpenAlexW3174873741

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.