Evidence map›Paper›PMID 34213425›Full record

ArticleSaudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association

Does restricting fluid volume impact post-ERCP pancreatitis in patient with heart disease?

Ko Tomishima, Shigeto Ishii, Toshio Fujisawa, Noboru Yatagai, Daishi Kabemura, Sho Sato, Nozomi Amano, Ayato Murata, Hironori Tsuzura, Shunsuke Sato and 5 more

Abstract read
In one paragraph

Article in Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. A risk score model for post-endoscopic retrograde cholangiopancreatography complications in elderly patients with choledocholithiasis.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Ko TomishimaDepartment of Gastroenterology, Graduate School of Medicine, Juntendo University; Department of Gastroenterology and Hepatology, Juntendo University Shizuoka Hospital, Tokyo, Japan.
Shigeto IshiiDepartment of Gastroenterology, Graduate School of Medicine, Juntendo University, Tokyo, Japan.
Toshio FujisawaDepartment of Gastroenterology, Graduate School of Medicine, Juntendo University, Tokyo, Japan.
Noboru YatagaiDepartment of Gastroenterology, Graduate School of Medicine, Juntendo University; Department of Gastroenterology and Hepatology, Juntendo University Shizuoka Hospital, Tokyo, Japan.
Daishi KabemuraDepartment of Gastroenterology, Graduate School of Medicine, Juntendo University; Department of Gastroenterology and Hepatology, Juntendo University Shizuoka Hospital, Tokyo, Japan.
Sho SatoDepartment of Gastroenterology and Hepatology, Juntendo University Shizuoka Hospital, Tokyo, Japan.
Nozomi AmanoDepartment of Gastroenterology and Hepatology, Juntendo University Shizuoka Hospital, Tokyo, Japan.
Ayato MurataDepartment of Gastroenterology and Hepatology, Juntendo University Shizuoka Hospital, Tokyo, Japan.
Hironori TsuzuraDepartment of Gastroenterology and Hepatology, Juntendo University Shizuoka Hospital, Tokyo, Japan.
Shunsuke SatoDepartment of Gastroenterology and Hepatology, Juntendo University Shizuoka Hospital, Tokyo, Japan.
Kouhei MatsumotoDepartment of Gastroenterology, Graduate School of Medicine, Juntendo University; Department of Gastroenterology and Hepatology, Juntendo University Shizuoka Hospital, Tokyo, Japan.
Yuji ShimadaDepartment of Gastroenterology and Hepatology, Juntendo University Shizuoka Hospital, Tokyo, Japan.
Takuya GendaDepartment of Gastroenterology and Hepatology, Juntendo University Shizuoka Hospital, Tokyo, Japan.
Akihito NagaharaDepartment of Gastroenterology, Graduate School of Medicine, Juntendo University; Department of Gastroenterology and Hepatology, Juntendo University Shizuoka Hospital, Tokyo, Japan.
Hiroyuki IsayamaDepartment of Gastroenterology, Graduate School of Medicine, Juntendo University, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

methodsTwo hundred and forty seven of 480 patients with naïve papilla undergoing therapeutic ERCP between April 2013 and March 2018 were enrolled for the study. The following patient characteristics were investigated: age, sex, body mass index, previous diseases (heart disease, renal failure, cerebrovascular disorders, coexisting malignancy and pulmonary disease), history of PEP, common bile duct diameter, diverticula and volume of fluid infused 24 hours after the procedure. All ERCP cases had naïve papilla and had undergone treatment.

resultsThe incidence of PEP was 8.5%. Significant differences were observed in the volume of fluid infused between patients without and with a history of heart disease (1,380 vs. 1,755 mL). The mean volume of the infused fluid was significantly lower in the PEP than non-PEP group (1,483 vs. 1,688 mL, P = 0.02). Moreover, PEP incidence differed according to a fluid infusion cutoff of 1,000 mL (7 vs. 11 cases of PEP in those with ≦1,000 mL and >1,000 mL fluid volume, respectively, P < 0.001).

conclusionRestricted fluid volume was a newly identified risk factor for PEP, particularly in patients with heart and renal diseases as comorbidities.

Indexed as

Heart DiseasesPancreatitisCholangiopancreatography, Endoscopic RetrogradeCommon Bile DuctHumansIncidenceRisk FactorsEndoscopic retrograde cholangiopancreatographyfluid volumepancreatitis

Identifiers

PMID34213425
PMCPMC8656333

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.