ArticleESC heart failure2021
Newly acquired complete right bundle branch block early after heart transplantation is associated with lower survival.
Article in ESC heart failure, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 10 citations in OpenAlex.
- Postoperative New-Onset Heart Block in Noncardiac Surgery: Model Development, Validation, and Long-Term Prognostic Analysis.JACC. Asia · 2026Article
- Left ventricular longitudinal function is reduced but partially compensated by increased radial function after heart transplantation.JHLT open · 2025Article
- Early Postoperative Cardiac Complications Following Heart Transplantation:.Galen medical journal · 2023Article
- Frequency, Risk Factors, and Clinical Outcomes of Late-Onset Atrial Flutter in Patients after Heart Transplantation.Journal of cardiovascular development and disease · 2022Article
- Pre-transplant Type 2 Diabetes Mellitus Is Associated With Higher Graft Failure and Increased 5-Year Mortality After Heart Transplantation.Frontiers in cardiovascular medicine · 2022Article
- Risk Factors, Treatment and Prognosis of Patients with Lung Cancer after Heart Transplantation.Life (Basel, Switzerland) · 2021Article
- Newly acquired complete right bundle branch block early after heart transplantation is associated with lower survival.ESC heart failure · 2021Article
- Atrial fibrillation before heart transplantation is a risk factor for post-transplant atrial fibrillation and mortality.ESC heart failure · 2021Article
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Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsRight bundle branch block (RBBB) after heart transplantation (HTX) is a common finding, but its impact on post-transplant survival remains uncertain. This study investigated the post-transplant outcomes of patients with complete RBBB (cRBBB) ≤ 30 days after HTX.
methodsThis registry study analysed 639 patients receiving HTX at Heidelberg Heart Center between 1989 and 2019. Patients were stratified by diagnosis of cRBBB ≤ 30 days after HTX. Analysis included recipient and donor data, medication, echocardiographic features, graft rejections, atrial fibrillation, heart rates, permanent pacemaker implantation and mortality after HTX including causes of death.
resultsOne hundred thirty-nine patients showed cRBBB ≤ 30 days after HTX (21.8%), 20 patients with pre-existing cRBBB in the donor heart (3.2%) and 119 patients with newly acquired cRBBB (18.6%). Patients with newly acquired cRBBB had a worse 1-year post-transplant survival (36.1%, P < 0.01) compared with patients with pre-existing cRBBB (85.0%) or without cRBBB (86.4%), along with a higher percentage of death due to graft failure (P < 0.01). Multivariate analysis indicated cRBBB ≤ 30 days after HTX as significant risk factor for 1-year mortality after HTX (HR: 2.20; 95% CI: 1.68-2.87; P < 0.01). Secondary outcomes showed a higher rate of an enlarged right atrium (P = 0.01), enlarged right ventricle (P < 0.01), reduced right ventricular function (P < 0.01), 30-day atrial fibrillation (P < 0.01) and 1-year permanent pacemaker implantation (P = 0.02) in patients with cRBBB after HTX.
conclusionsNewly acquired cRBBB early after HTX is associated with increased post-transplant mortality.
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