Evidence map›Paper›PMID 34213074›Full record

ArticleThe Kaohsiung journal of medical sciences2021

Inhibition of suppressor of cytokine signaling-3 affects mesangial cell proliferation and cell cycle in mesangioproliferative glomerulonephritis.

Min Liu, Ya-Chao Wang, Jun Zhou

Open access · goldAbstract read
In one paragraph

Article in The Kaohsiung journal of medical sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 0 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Min LiuDepartment of Nephrology, Wuhan Asia General Hospital, Wuhan, China.
Ya-Chao WangDepartment of Nephrology, Wuhan Asia General Hospital, Wuhan, China.
Jun ZhouDepartment of Paediatrics, Xiaogan Central Hospital Affiliated with Wuhan University of Science and Technology, Xiaogan, Hubei, China.ORCID https://orcid.org/0000-0002-6024-0511
Wuhan University · CNThe Central Hospital of Xiao gan · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To explore the role of suppressor of cytokine signaling-3 (SOCS-3) in mesangial proliferative glomerulonephritis (MsPGN). SOCS-3 expression in kidney tissues from MsPGN patients was detected using immunohistochemistry. Double immunofluorescence staining was performed to investigate the localization of SOCS-3 with α-SMA in glomeruli. Heminephrectomized wild-type (WT) and SOCS-3

Indexed as

AnimalsCase-Control StudiesCell CycleCell LineCell ProliferationCollagenGlomerular MesangiumGlomerulonephritisHumansKidneyMaleMiceMice, KnockoutSuppressor of Cytokine Signaling 3 ProteinCollagenSOCS3 protein, humanSuppressor of Cytokine Signaling 3 Proteincell cycleMsPGNPCNAproliferationSOCS-3

Identifiers

PMID34213074
PMCPMC11896534
OpenAlexW3177201285

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.