Evidence map›Paper›PMID 34213073›Full record

Observational studyClinical and translational science2021

COVID-19 vaccine hesitancy: Race/ethnicity, trust, and fear.

Don E Willis, Jennifer A Andersen, Keneshia Bryant-Moore, James P Selig, Christopher R Long, Holly C Felix, Geoffrey M Curran, Pearl A McElfish

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Clinical and translational science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 213 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
213citing papers in PubMed, 2 pooled it
41.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

213 citing papers in PubMed, 2 syntheses or guidelines pooled it, 383 citations in OpenAlex.

  1. Pooled it
  2. The Role of Trust in COVID-19 Vaccine Acceptance: Considerations from a Systematic Review.International journal of environmental research and public health · 2022
    Pooled it
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  18. Interventions to Improve COVID-19 Vaccine Hesitancy.Rheumatic diseases clinics of North America · 2025
    Review
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153 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Don E WillisCollege of Medicine, University of Arkansas for Medical Sciences Northwest, Fayetteville, Arkansas, USA.
Jennifer A AndersenCollege of Medicine, University of Arkansas for Medical Sciences Northwest, Fayetteville, Arkansas, USA.ORCID 0000-0001-6809-892X
Keneshia Bryant-MooreFay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
James P SeligFay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Christopher R LongCollege of Medicine, University of Arkansas for Medical Sciences Northwest, Fayetteville, Arkansas, USA.ORCID 0000-0002-0574-7790
Holly C FelixFay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Geoffrey M CurranCollege of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Pearl A McElfishCollege of Medicine, University of Arkansas for Medical Sciences Northwest, Fayetteville, Arkansas, USA.ORCID 0000-0002-4033-6241
University of Arkansas for Medical Sciences · US

Funding

Expanding Translational Research in ArkansasUL1TR003107 · NCATS · UNIV OF ARKANSAS FOR MED SCIS · PI JAMES, LAURA P · 2019 to 2023
$21.6M
NCATS NIH HHS UL1 TR003107
6 · The paper itself

Abstract

Understanding and minimizing coronavirus disease 2019 (COVID-19) vaccine hesitancy is critical to population health and minimizing health inequities, which continue to be brought into stark relief by the pandemic. We investigate questions regarding vaccine hesitancy in a sample (n = 1205) of Arkansas adults surveyed online in July/August of 2020. We examine relationships among sociodemographics, COVID-19 health literacy, fear of COVID-19 infection, general trust in vaccines, and COVID-19 vaccine hesitancy using bivariate analysis and a full information maximum likelihood (FIML) logistic regression model. One in five people (21,21.86%) reported hesitancy to take a COVID-19 vaccine. Prevalence of COVID-19 vaccine hesitancy was highest among Black/African Americans (50.00%), respondents with household income less than $25K (30.68%), some college (32.17%), little to no fear of infection from COVID-19 (62.50%), and low trust in vaccines in general (55.84%). Odds of COVID-19 vaccine hesitancy were 2.42 greater for Black/African American respondents compared to White respondents (p < 0.001), 1.67 greater for respondents with some college/technical degree compared to respondents with a 4-year degree (p < 0.05), 5.48 greater for respondents with no fear of COVID-19 infection compared to those who fear infection to a great extent (p < 0.001), and 11.32 greater for respondents with low trust in vaccines (p < 0.001). Sociodemographic differences in COVID-19 vaccine hesitancy raise concerns about the potential of vaccine implementation to widen existing health disparities in COVID-19 related infections, particularly among Black/African Americans. Fear of infection and general mistrust in vaccines are significantly associated with vaccine hesitancy.

Indexed as

AdolescentAdultAgedAged, 80 and overBlack or African AmericanCOVID-19COVID-19 VaccinesFearFemaleHispanic or LatinoHumansMaleMass VaccinationMiddle AgedPandemicsPatient Acceptance of Health CareCOVID-19 Vaccines

Identifiers

PMID34213073
PMCPMC8444681
OpenAlexW3175390354

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.