Evidence map›Paper›PMID 34213066›Full record

ArticleAutism research : official journal of the International Society for Autism Research2021

Health profiles of adults with autism spectrum disorder: Differences between women and men.

Leann Smith DaWalt, Julie Lounds Taylor, Arezoo Movaghar, Jinkuk Hong, Bryan Kim, Murray Brilliant, Marsha R Mailick

Open access · greenAbstract read
In one paragraph

Article in Autism research : official journal of the International Society for Autism Research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 32 citations in OpenAlex.

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  4. The healthcare experiences of middle and older age autistic women in the United Kingdom.Autism : the international journal of research and practice · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Leann Smith DaWaltWaisman Center, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0002-0376-4095
Julie Lounds TaylorDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Arezoo MovagharWaisman Center, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Jinkuk HongWaisman Center, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Bryan KimWaisman Center, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Murray BrilliantWaisman Center, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Marsha R MailickWaisman Center, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0001-6548-2096
University of Wisconsin–Madison · USVanderbilt University Medical Center · US

Funding

Overall: Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at VanderbiltP50HD103537 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Jeffrey L Neul · 2020 to 2026
$10.3M
Research Project: Sensory and Multisensory Contributions to AutismU54HD083211 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DYKENS, ELISABETH MAY · 2015 to 2019
$7.1M
Waisman Intellectual and Developmental Disabilities Research Center Down Syndrome RegistryU54HD090256 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI CHANG, QIANG · 2016 to 2020
$6.0M
Women with Autism Spectrum Disorders during Adolescence and Adulthood: Unique and Common VulnerabilitiesR03MH112783 · NIMH · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DAWALT, LEANN SMITH, TAYLOR, JULIE LOUNDS · 2017 to 2018
$170k
NICHD NIH HHS P50 HD103537NICHD NIH HHS U54 HD083211NICHD NIH HHS U54 HD090256NIMH NIH HHS R03 MH112783
6 · The paper itself

Abstract

The purpose of the present study was to investigate the hypothesis that women with autism have poorer health compared with men with autism, and compared with women without autism. Utilizing electronic health records drawn from a single health care system serving over 2 million individuals, 2119 adults with diagnosed autism spectrum disorders were compared with age- and sex-matched controls. When considering health care utilization, we found evidence of multiplicative risk for conditions within some domains (i.e., nutrition conditions, neurologic disease, psychiatric conditions, and sleep disorders) such that women with autism spectrum disorder (ASD) experienced double jeopardy-meaning they had greater rates of health care utilization within a domain than what would separately be expected by virtue of being a woman and having ASD. For other domains (i.e., endocrine disorders, gastrointestinal disorders), the risk was additive such that being a female and having ASD were both associated with higher health care utilization, but there were no significant interaction effects. It was only with respect to one domain (cardiovascular) that rates of health care utilization were reflective of neither ASD diagnosis nor sex. Overall, our findings suggest that women with ASD are a vulnerable subgroup with high levels of health care utilization. LAY SUMMARY: This study asked whether women with autism have poorer health compared with men with autism, and compared with women without autism. To answer this question, we used data from electronic health records. We found that women with autism spectrum disorder (ASD) were at the greatest risk for health problems such as nutrition conditions, neurologic disease, psychiatric conditions, and sleep disorders. More research on health of women with ASD is needed.

Indexed as

Autism Spectrum DisorderAutistic DisorderSleep Wake DisordersAdultElectronic Health RecordsFemaleHumansMaleadultselectronic health recordshealthhealth care utilizationsex differences

Identifiers

PMID34213066
PMCPMC8592037
OpenAlexW3173811501

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.