Evidence map›Paper›PMID 34212873›Full record

ArticleJournal of synchrotron radiation2021

Millisecond timescale reactions observed via X-ray spectroscopy in a 3D microfabricated fused silica mixer.

Diego A Huyke, Ashwin Ramachandran, Oscar Ramirez-Neri, Jose A Guerrero-Cruz, Leland B Gee, Augustin Braun, Dimosthenis Sokaras, Brenda Garcia-Estrada, Edward I Solomon, Britt Hedman and 4 more

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of synchrotron radiation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Diego A HuykeStanford University, Stanford, CA 94305, USA.ORCID 0000-0002-8335-6613
Ashwin RamachandranStanford University, Stanford, CA 94305, USA.ORCID 0000-0002-2512-8401
Oscar Ramirez-NeriUniversity of Guadalajara, 44430 Guadalajara, Mexico.ORCID 0000-0003-4658-8850
Jose A Guerrero-CruzUniversity of Guadalajara, 44430 Guadalajara, Mexico.ORCID 0000-0003-3078-4048
Leland B GeeStanford University, Stanford, CA 94305, USA.ORCID 0000-0002-5817-3997
Augustin BraunStanford University, Stanford, CA 94305, USA.ORCID 0000-0002-9487-5769
Dimosthenis SokarasStanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Stanford University, Menlo Park, CA 94025, USA.ORCID 0000-0001-8117-1933
Brenda Garcia-EstradaUniversity of Guadalajara, 44430 Guadalajara, Mexico.
Edward I SolomonStanford University, Stanford, CA 94305, USA.ORCID 0000-0003-0291-3199
Britt HedmanStanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Stanford University, Menlo Park, CA 94025, USA.
Mario U Delgado-JaimeUniversity of Guadalajara, 44430 Guadalajara, Mexico.ORCID 0000-0003-4680-2001
Daniel P DePonteLinac Coherent Light Source, SLAC National Accelerator Laboratory, Stanford University, Menlo Park, CA 94025, USA.ORCID 0000-0003-0404-7511
Thomas KrollStanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Stanford University, Menlo Park, CA 94025, USA.ORCID 0000-0003-2176-6905
Juan G SantiagoStanford University, Stanford, CA 94305, USA.ORCID 0000-0001-8652-5411

Funding

X-ray Absorption Spectroscopy (XAS) pp.711-759P41GM103393 · NIGMS · STANFORD UNIVERSITY · PI HODGSON, KEITH O · 2012 to 2019
$30.6M
SPECTROSCOPIC STUDIES OF NONHEME IRON ENZYMESR01GM040392 · NIGMS · STANFORD UNIVERSITY · PI SOLOMON, EDWARD I · 1988 to 2021
$8.6M
Spectroscopic Characterization of Oxygen Intermediates in Non-heme and Heme Iron EnzymesR35GM145202 · NIGMS · STANFORD UNIVERSITY · PI EDWARD I SOLOMON · 2022 to 2026
$2.0M
Electronic Structure of Heme Enzyme Intermediates from Resonant Inelastic X-ray Scattering and L-Edge X-ray Absorption SpectroscopyF32GM122194 · NIGMS · STANFORD UNIVERSITY · PI GEE, LELAND BRUCE · 2017 to 2020
$227k
National Institute of Health GM-40392NIGMS NIH HHS F32 GM122194NIGMS NIH HHS P41 GM103393NIGMS NIH HHS R01 GM040392NIGMS NIH HHS R35 GM145202NIH National Institute of General Medical Sciences F32GM122194NIH National Institute of General Medical Sciences P41GM103393US Department of Energy, Office of Science, Office of Basic Energy Sciences DE-AC02-76SF00515
6 · The paper itself

Abstract

Determination of electronic structures during chemical reactions remains challenging in studies which involve reactions in the millisecond timescale, toxic chemicals, and/or anaerobic conditions. In this study, a three-dimensionally (3D) microfabricated microfluidic mixer platform that is compatible with time-resolved X-ray absorption and emission spectroscopy (XAS and XES, respectively) is presented. This platform, to initiate reactions and study their progression, mixes a high flow rate (0.50-1.5 ml min

Indexed as

3D microfabricationkineticsmicrofluidicsmixingX-ray spectroscopy

Identifiers

PMID34212873
PMCPMC8284405

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.