Evidence map›Paper›PMID 34212768›Full record

ReviewJournal of the American Heart Association2021

Cangrelor: Clinical Data, Contemporary Use, and Future Perspectives.

Leonardo De Luca, Philippe Gabriel Steg, Deepak L Bhatt, Davide Capodanno, Dominick J Angiolillo

Open access · goldAbstract readReview
In one paragraph

Review in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 3 pooled it
9.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 3 syntheses or guidelines pooled it, 82 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Safety and Efficacy of Cangrelor in Acute Coronary Syndromes: A Systematic Review and Network Meta-Analysis.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2024
    Pooled it
  4. Article
  5. Oral P2YInternational journal of cardiology. Heart & vasculature · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. The role of cangrelor in acute and high-risk PCI settings.European heart journal. Cardiovascular pharmacotherapy · 2025
    Review
  14. Article
  15. Article
  16. 2024 EACTS/EACTAIC Guidelines on patient blood management in adult cardiac surgery in collaboration with EBCP.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2025
    Article
  17. Article
  18. Review
  19. Repurposing FDA-Approved Agents to Develop a PrototypePharmaceuticals (Basel, Switzerland) · 2025
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 4 countries.

Leonardo De LucaDivision of Cardiology Department of Cardiosciences Azienda Ospedaliera San Camillo-Forlanini Roma Italy.
Philippe Gabriel StegFACT (French Alliance for Cardiovascular Trials) and INSERM U-1148 AP-HPHôpital BichatUniversité de Paris France.
Deepak L BhattBrigham and Women's Hospital Heart and Vascular Center Harvard Medical School Boston MA.
Davide CapodannoDivision of Cardiology A.O.U. Policlinico "G. Rodolico-San Marco" University of Catania Catania Italy.
Dominick J AngiolilloDivision of Cardiology University of Florida College of Medicine Jacksonville FL.
Azienda Ospedaliera San Camillo-Forlanini · ITBrigham and Women's Hospital · USInserm · FRUniversity of Catania · ITUniversity of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cangrelor is the only currently available intravenous platelet P2Y

Indexed as

Percutaneous Coronary InterventionAcute Coronary SyndromeAdenosine MonophosphateAnimalsHumansPlatelet Aggregation InhibitorsPurinergic P2Y Receptor AntagonistsRisk AssessmentRisk FactorsThrombosisTreatment OutcomeAdenosine MonophosphatecangrelorPlatelet Aggregation InhibitorsPurinergic P2Y Receptor Antagonistsacute coronary syndromescangrelorpercutaneous coronary intervention

Identifiers

PMID34212768
PMCPMC8403274
OpenAlexW3177428554

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.