ArticleJournal of the American Heart Association2021
Association of Nonacute Opioid Use and Cardiovascular Diseases: A Scoping Review of the Literature.
Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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Who cites it
14 citing papers in PubMed.
- Elevated Cardiovascular Risk and Mortality in Type 2 Diabetes Mellitus Patients With Cannabis, Opioid, and Cocaine Use Disorders.Diabetes, obesity & metabolism · 2026Article
- Opioid overdose and cardiovascular disease-related mortality: a retrospective analysis using real-world data from the USA, 1999-2023.Frontiers in cardiovascular medicine · 2026Article
- Article
- Association of Opioid Prescription with Major Adverse Cardiovascular Events: Nationwide Cohort Study.Journal of clinical medicine · 2025Article
- A Review of Cardiovascular Diseases in Substance Use Disorders: Current Knowledge and Future Perspectives.Addiction & health · 2025Review
- The Association of Prescribed Opioids and Incident Cardiovascular Disease.The journal of pain · 2024Article
- Prevalence of major non-communicable diseases and their associated risk factors in Afghanistan: a systematic review and meta-analysis.Therapeutic advances in chronic disease · 2024Review
- The opioid tramadol blocks the cardiac sodium channel Nav1.5 in HEK293 cells.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023Article
- Gender differences in physical morbidity in opioid agonist treatment patients: population-based cohort studies from the Czech Republic and Norway.Substance abuse treatment, prevention, and policy · 2023Article
- Prenatal Morphine Exposure Increases Cardiovascular Disease Risk and Programs Neurogenic Hypertension in the Adult Offspring.Hypertension (Dallas, Tex. : 1979) · 2023Article
- Association of opioid use disorder with outcomes of hospitalizations for acute myocardial infarction in the United States.Clinics (Sao Paulo, Brazil) · 2023Article
- Management of Psychiatric Disorders in Patients with Cardiovascular Diseases.Indian journal of psychiatry · 2022Article
- Article
- Association of Nonacute Opioid Use and Cardiovascular Diseases: A Scoping Review of the Literature.Journal of the American Heart Association · 2021Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND In this scoping review, we identified and reviewed 23 original articles from the PubMed database that investigated the relationship between nonacute opioid use (NOU) and cardiovascular outcomes. METHODS AND RESULTS We defined NOU to include both long-term opioid therapy and opioid use disorder. We summarized the association between NOU and 5 classes of cardiovascular disease, including infective endocarditis, coronary heart disease (including myocardial infarction), congestive heart failure, cardiac arrythmia (including cardiac arrest), and stroke. The most commonly studied outcomes were coronary heart disease and infective endocarditis. There was generally consistent evidence of a positive association between community prevalence of injection drug use (with opioids being the most commonly injected type of drug) and community prevalence of infective endocarditis, and between (primarily medically indicated) NOU and myocardial infarction. There was less consensus about the relationship between NOU and congestive heart failure, cardiac arrhythmia, and stroke. CONCLUSIONS There is a dearth of high-quality evidence on the relationship between NOU and cardiovascular disease. Innovative approaches to the assessment of opioid exposure over extended periods of time will be required to address this need.
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