Evidence map›Paper›PMID 34212739›Full record

ArticleAfrican journal of primary health care & family medicine2021

Opinion and uptake of chloroquine for treatment of COVID-19 during the mandatory lockdown in the sub-Saharan African region.

Uchechukwu L Osuagwu, Obinna Nwaeze, Godwin Ovenseri-Ogbomo, Richard Oloruntoba, Bernadine Ekpenyong, Khathutshelo P Mashige, Chikasirimobi Timothy, Tanko Ishaya, Raymond Langsi, Deborah Charwe and 3 more

Open access · goldAbstract read
In one paragraph

Article in African journal of primary health care & family medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 11 institutions in 8 countries.

Uchechukwu L OsuagwuSchool of Medicine, Diabetes, Obesity and Metabolism Translational Research Unit, Western Sydney University, Campbelltown, New South Wales, Australia; and, African Eye and Public Health Research Initiative, African Vision Research Institute, Discipline of Optometry, University of KwaZulu-Natal, Durban, South Africa. o_leviuche@hotmail.com.
Obinna Nwaeze
Godwin Ovenseri-Ogbomo
Richard Oloruntoba
Bernadine Ekpenyong
Khathutshelo P Mashige
Chikasirimobi Timothy
Tanko Ishaya
Raymond Langsi
Deborah Charwe
Emmanuel Kwasi Abu
Miner A Chundung
Kingsley E Agho
University of Jos · NGAfrica Health Research Institute · ZACamden and Campbelltown Hospitals · AUCurtin University · AUMasinde Muliro University of Science and Technology · KETanzania Food and Nutrition Center · TZUniversity of Bamenda · CMUniversity of Benin · NGUniversity of Calabar · NGUniversity of Cape Coast · GHUniversity of KwaZulu-Natal · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAs the search for effective treatment of coronavirus disease 2019 (COVID-19) infection continues, the public opinion around the potential use of chloroquine (CQ) in treating COVID-19 remains mixed.

aimTo examine opinion and uptake of CQ for treating COVID-19 in the sub-Saharan African (SSA) region.

settingThis study was conducted through an online survey software titled SurveyMonkey.

methodsAnonymous online survey of 1829 SSA countries was conducted during the lockdown period using Facebook, WhatsApp and authors' networks. Opinion and uptake of CQ for COVID-19 treatment were assessed using multivariate analyses.

resultsAbout 14% of respondents believed that CQ could treat COVID-19 and of which, 3.2% took CQ for COVID-19 treatment. Multivariate analyses revealed that respondents from Central (adjusted odds ratios [aOR]: 2.54, 95% confidence interval [CI] 1.43, 4.43) and West Africa (aOR: 1.79, 95% CI 1.15, 2.88) had higher odds of believing that CQ could treat COVID-19. Respondents from East Africa reported higher odds for uptake of CQ for COVID-19 than Central, Western and Southern Africans. Knowledge of the disease and compliance with the public health advice were associated with both belief and uptake of CQ for COVID-19 treatment.

conclusionCentral and West African respondents were more likely to believe in CQ as a treatment for COVID-19 whilst the uptake of the medication during the pandemic was higher amongst East Africans. Future intervention discouraging the unsupervised use of CQ should target respondents from Central, West and East African regions.

Indexed as

COVID-19 Drug TreatmentAdolescentAdultAfrica South of the SaharaChloroquineCommunicable Disease ControlFemaleHealth Knowledge, Attitudes, PracticeHumansHydroxychloroquineMaleMiddle AgedPandemicsPublic OpinionSARS-CoV-2Surveys and QuestionnairesChloroquineHydroxychloroquineAfricachloroquine hydrochloridecoronaviruspoisoningsub-Saharan Africa

Identifiers

PMID34212739
PMCPMC8252178
OpenAlexW3171587245

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.