ArticleJournal of applied clinical medical physics2021
Evaluation of the correlation between dosimetric, geometric, and technical parameters of radiosurgery planning for multiple brain metastases.
Article in Journal of applied clinical medical physics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Optimizing anisotropic margins in single-isocenter multiple brain metastases radiosurgery using regressor strategies: A multi-institutional validation study.Journal of applied clinical medical physics · 2025Article
- Tumor-driven SRS VMAT planning: Regression models for intermediate and low dose spillage.Journal of applied clinical medical physics · 2025Article
- Treatment of patients with multiple brain metastases by isolated radiosurgery: Toxicity and survival.World journal of clinical oncology · 2023Article
- Evaluation of the correlation between dosimetric, geometric, and technical parameters of radiosurgery planning for multiple brain metastases.Journal of applied clinical medical physics · 2021Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate the correlation between dosimetric, geometric, and technical parameters for radiosurgery planning of multiple brain metastasis treatments treated with a linear accelerator with volumetric modulated arc therapy (VMAT) technique. MATERIALS AND
methodsData were collected retrospectively from 55 patients who underwent radiosurgery in a single institution from August 2017 to February 2020. Patients presented 4-21 brain metastases were treated with a single fraction with doses between 18 and 20 Gy. Dosimetric variables were collected including V5Gy, V8Gy, V10Gy, V12Gy, V14Gy, conformity index (CI), heterogeneity index (HI), maximum dose (Dmax), and the CI_R50. Geometric variables including the number of lesions, target volumes, the smallest target volume, the largest target volume, and the distance between the isocenter and the most distant lesion (DIL) and technical variables such as the numbers of total arcs, noncoplanar arcs, and isocenters were collected for analysis.
resultsThe number of lesions had a moderate positive correlation with V5Gy, V8Gy, V10Gy, V12Gy, V14Gy, HI, Dmax, and with the number of total arcs. The target volumes had a positive medium-high correlation with V5Gy, V8Gy, V10Gy, V12Gy, V14Gy, and moderate positive correlation with HI, Dmax, number of arcs and noncoplanar arcs. The CI and CI_R50 had a negative correlation with all volumes related to the target: the target volumes, the smallest, and the largest lesion. A positive correlation was observed between the distance of the isocenter and the most DIL with V5Gy, V8Gy, V10Gy, V12Gy, V14Gy, HI, Dmax, and the number of isocenters.
conclusionIt was found that the number of lesions and the target volumes are good predictors of dosimetric indexes of plan evaluation and that the distance between the isocenter and the most DIL harms them.
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